loading...| Preferred Name |
Alkylating Agent |
|
| Synonyms |
Alkylating Agent Alkylating Agents alkylating agent Alkylator |
|
| Definitions |
Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C223 |
|
| ALT_DEFINITION |
A type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell growth. |
|
| CHEBI_ID |
CHEBI:22333 |
|
| code |
C223 |
|
| DEFINITION |
Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth. |
|
| FULL_SYN |
Alkylating Agent Alkylating Agents alkylating agent Alkylator |
|
| label |
Alkylating Agent |
|
| Legacy Concept Name |
Alkylating_Agent |
|
| Preferred_Name |
Alkylating Agent |
|
| prefixIRI |
Thesaurus:C223 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C0002073 |
|
| subClassOf |