National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ribonucleotide Reductase Inhibitor

Synonyms

Ribonucleotide Reductase Inhibitor

Definitions

Any substance that inhibits ribonucleotide reductase, an enzyme that catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleotide diphosphate precursors for de novo DNA synthesis. Inhibition of ribonucleotide reductase can cause inhibition of DNA synthesis and cell growth.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2150

code

C2150

DEFINITION

Any substance that inhibits ribonucleotide reductase, an enzyme that catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleotide diphosphate precursors for de novo DNA synthesis. Inhibition of ribonucleotide reductase can cause inhibition of DNA synthesis and cell growth.

FULL_SYN

Ribonucleotide Reductase Inhibitor

label

Ribonucleotide Reductase Inhibitor

Legacy Concept Name

Ribonucleotide_Reductase_Inhibitor

Preferred_Name

Ribonucleotide Reductase Inhibitor

prefixIRI

Thesaurus:C2150

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C2746039

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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http://purl.obolibrary.org/obo/NCIT_C2150 BERO LOOM