National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Enfuvirtide

Synonyms

Enfuvirtide

ENFUVIRTIDE

DP178

Fuzeon

T-20

Definitions

A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral envelope glycoprotein, thereby preventing conformational changes required for fusion of viral and cellular membranes and preventing the virus from entering a host cell.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2105

CAS_Registry

159519-65-0

CHEBI_ID

CHEBI:608828

Chemical_Formula

C204H301N51O64

code

C2105

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral envelope glycoprotein, thereby preventing conformational changes required for fusion of viral and cellular membranes and preventing the virus from entering a host cell.

FDA_UNII_Code

19OWO1T3ZE

FULL_SYN

Enfuvirtide

ENFUVIRTIDE

DP178

Fuzeon

T-20

label

Enfuvirtide

Legacy Concept Name

T-20

Preferred_Name

Enfuvirtide

prefixIRI

Thesaurus:C2105

Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance

UMLS_CUI

C0537439

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1660

Delete Subject Author Type Created
No notes to display