Preferred Name |
Enfuvirtide |
|
Synonyms |
Enfuvirtide ENFUVIRTIDE DP178 Fuzeon T-20 |
|
Definitions |
A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral envelope glycoprotein, thereby preventing conformational changes required for fusion of viral and cellular membranes and preventing the virus from entering a host cell. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2105 |
|
CAS_Registry |
159519-65-0 |
|
CHEBI_ID |
CHEBI:608828 |
|
Chemical_Formula |
C204H301N51O64 |
|
code |
C2105 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral envelope glycoprotein, thereby preventing conformational changes required for fusion of viral and cellular membranes and preventing the virus from entering a host cell. |
|
FDA_UNII_Code |
19OWO1T3ZE |
|
FULL_SYN |
Enfuvirtide ENFUVIRTIDE DP178 Fuzeon T-20 |
|
label |
Enfuvirtide |
|
Legacy Concept Name |
T-20 |
|
Preferred_Name |
Enfuvirtide |
|
prefixIRI |
Thesaurus:C2105 |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
UMLS_CUI |
C0537439 |
|
subClassOf |