National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Cyclic AMP

Synonyms

3'5'-cyclic ester of AMP

ADENOSINE CYCLIC PHOSPHATE

Adenosine Cyclic 3',5'-Phosphate

Adenosine Cyclic 3',5'-(Hydrogen Phosphate)

Adenosine Cyclic 3':5'-Monophosphate

Cyclic Adenosine Monophosphate

Cyclic AMP

cAMP

Definitions

A second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C208

CAS_Registry

60-92-4

CHEBI_ID

CHEBI:17489

Chemical_Formula

C10H12N5O6P

code

C208

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways.

Display_Name

Cyclic AMP

FDA_UNII_Code

E0399OZS9N

FULL_SYN

3'5'-cyclic ester of AMP

ADENOSINE CYCLIC PHOSPHATE

Adenosine Cyclic 3',5'-Phosphate

Adenosine Cyclic 3',5'-(Hydrogen Phosphate)

Adenosine Cyclic 3':5'-Monophosphate

Cyclic Adenosine Monophosphate

Cyclic AMP

cAMP

label

Cyclic AMP

Legacy Concept Name

Cyclic_AMP

NSC Number

94017

Preferred_Name

Cyclic AMP

prefixIRI

Thesaurus:C208

Semantic_Type

Nucleic Acid, Nucleoside, or Nucleotide

UMLS_CUI

C0001455

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1903

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