loading...| Preferred Name |
Histamine Dihydrochloride |
|
| Synonyms |
2-(1-H-imidazol-4-yl) Ethylamine Dihydrochloride Histamine Dihydrochloride HISTAMINE DIHYDROCHLORIDE Histamine Hydrochloride histamine dihydrochloride Histamine dihydrochloride Ceplene Maxamine |
|
| Definitions |
The hydrochloride salt form of histamine, with potential immunomodulatory and antineoplastic activities. Upon administration, histamine targets, binds to and activates histamine receptors. Depending on the amount of histamine administered and the type of receptor that is activated, histamine may exert a wide variety of activities. These can range from pro-tumorigenic to anti-tumor effects and may modulate the immune system to exert anti-tumor immune effects or may contribute to an inflammatory response. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1734 |
|
| ALT_DEFINITION |
A substance being studied in the treatment of some types of cancer and other conditions. When used together with interleukin-2, histamine dihydrochloride may help some immune cells find and kill tumor cells. It is a type of biological response modifier. |
|
| CAS_Registry |
56-92-8 |
|
| Chemical_Formula |
C5H9N3.2HCl |
|
| code |
C1734 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt form of histamine, with potential immunomodulatory and antineoplastic activities. Upon administration, histamine targets, binds to and activates histamine receptors. Depending on the amount of histamine administered and the type of receptor that is activated, histamine may exert a wide variety of activities. These can range from pro-tumorigenic to anti-tumor effects and may modulate the immune system to exert anti-tumor immune effects or may contribute to an inflammatory response. |
|
| FDA_UNII_Code |
3POA0Q644U |
|
| FULL_SYN |
2-(1-H-imidazol-4-yl) Ethylamine Dihydrochloride Histamine Dihydrochloride HISTAMINE DIHYDROCHLORIDE Histamine Hydrochloride histamine dihydrochloride Histamine dihydrochloride Ceplene Maxamine |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Histamine Dihydrochloride |
|
| Legacy Concept Name |
Histamine_Dihydrochloride |
|
| NCI_Drug_Dictionary_ID |
42918 |
|
| NSC Number |
257873 |
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| PDQ_Closed_Trial_Search_ID |
42918 |
|
| PDQ_Open_Trial_Search_ID |
42918 |
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| Preferred_Name |
Histamine Dihydrochloride |
|
| prefixIRI |
Thesaurus:C1734 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0543456 |
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| subClassOf |