loading...| Preferred Name |
Insulin Receptor |
|
| Synonyms |
Antigen CD220 CD220 Antigen Insulin Receptor EC 2.7.10.1 CD220 INSR IR |
|
| Definitions |
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17072 |
|
| code |
C17072 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis. |
|
| DesignNote |
Insulin receptor is cleaved to generate and alpha chain and a beta chain. The mature receptor is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. (UniProt) |
|
| Display_Name |
Insulin Receptor |
|
| FULL_SYN |
Antigen CD220 CD220 Antigen Insulin Receptor EC 2.7.10.1 CD220 INSR IR |
|
| label |
Insulin Receptor |
|
| Legacy Concept Name |
Insulin_Receptor |
|
| OMIM_Number |
147670 |
|
| Preferred_Name |
Insulin Receptor |
|
| prefixIRI |
Thesaurus:C17072 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme Receptor |
|
| Swiss_Prot |
P06213 |
|
| UMLS_CUI |
C1448132 |
|
| subClassOf |