National Cancer Institute Thesaurus

Last uploaded: July 29, 2019
Preferred Name

Mutation

Synonyms

Genetic Alteration

Mutated

Mutation

Genetic Change

mutation

Definitions

Any transmissible change in the genetic material of an organism, which can result from radiation, viral infection, transposition, treatment with mutagenic chemicals and errors during DNA replication or meiosis. As many of the simpler alterations to DNA may be repaired, such changes are only heritable once the change is fixed in the DNA by the process of replication. Mutations may be associated with genetic diversity or with pathologies including cancer.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16885

Obsolete

true

ALT_DEFINITION

Any change in the DNA of a cell. Mutations may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment. Mutations can be harmful, beneficial, or have no effect. If they occur in cells that make eggs or sperm, they can be inherited; if mutations occur in other types of cells, they are not inherited. Certain mutations may lead to cancer or other diseases.

code

C16885

Concept_Status

Retired_Concept

DEFINITION

Any transmissible change in the genetic material of an organism, which can result from radiation, viral infection, transposition, treatment with mutagenic chemicals and errors during DNA replication or meiosis. As many of the simpler alterations to DNA may be repaired, such changes are only heritable once the change is fixed in the DNA by the process of replication. Mutations may be associated with genetic diversity or with pathologies including cancer.

deprecated

true

DesignNote

Wed Jun 16 11:17:20 EDT 2010 - See 'Mutation_Abnormality'

FULL_SYN

Genetic Alteration

Mutated

Mutation

Genetic Change

mutation

label

Mutation

Legacy_Concept_Name

Mutation

Preferred_Name

Mutation

prefixIRI

ncit:C16885

Semantic_Type

Cell or Molecular Dysfunction

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C95421

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#G05.365.590 RH-MESH LOOM
http://d-nb.info/gnd/4170883-0 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/MSH/D009154 HUPSON LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/MI_0118 MI LOOM
http://purl.obolibrary.org/obo/ODGI.owl#Mutation OGDI LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 OGSF LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 VDOT LOOM
http://purl.obolibrary.org/obo/OGI_0000088 OGI LOOM
http://www.projecthalo.com/aura#Mutation AURA LOOM
http://localhost/plosthes.2017-1#2387 PLOSTHES LOOM
http://purl.obolibrary.org/obo/GENO_0000492 GENO LOOM
http://purl.obolibrary.org/obo/GENO_0000492 GENO LOOM
http://purl.obolibrary.org/obo/GENO_0000492 GENO LOOM
http://purl.bioontology.org/net/brunel/panda#Mutation PANDA LOOM
http://purl.obolibrary.org/obo/IDOMAL_50000026 IDOMAL LOOM
http://purl.obolibrary.org/obo/IDOMAL_50000026 IDODEN LOOM
http://purl.bioontology.org/ontology/LNC/LP32514-9 LOINC LOOM
http://id.loc.gov/authorities/subjects/sh00006798 FAST-TOPICAL LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
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http://bioportal.bioontology.org/ontologies/txpo/TXPO_0001985 TXPO LOOM
http://scai.fraunhofer.de/AlzheimerOntology#mutation ADO LOOM
http://www.bootstrep.eu/ontology/GRO#Mutation GRO LOOM
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http://sweetontology.net/phenEcology/Mutation SWEET LOOM
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http://purl.jp/bio/4/id/200906045227981407 IOBC LOOM
http://purl.jp/bio/4/id/200906045227981407 IOBC LOOM
http://purl.jp/bio/4/id/200906045227981407 IOBC LOOM
http://doe-generated-ontology.com/OntoAD#C0026882 ONTOAD LOOM