loading...| Preferred Name |
HMG-CoA Reductase Inhibitor |
| Synonyms |
hydroxymethylglutaryl-coenzyme A reductase inhibitor statin HMG-CoA Reductase Inhibitor Statin Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors HMG-CoA reductase inhibitor |
| Definitions |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1655 |
| ALT_DEFINITION |
Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer. |
| CHEBI_ID |
CHEBI:35664 |
| code |
C1655 |
| DEFINITION |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. |
| FULL_SYN |
hydroxymethylglutaryl-coenzyme A reductase inhibitor statin HMG-CoA Reductase Inhibitor Statin Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors HMG-CoA reductase inhibitor |
| label |
HMG-CoA Reductase Inhibitor |
| Legacy_Concept_Name |
HMG-CoA_Reductase_Inhibitor |
| Preferred_Name |
HMG-CoA Reductase Inhibitor |
| prefixIRI |
ncit:C1655 |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C0360714 |
| subClassOf |