Preferred Name

HMG-CoA Reductase Inhibitor

Synonyms

hydroxymethylglutaryl-coenzyme A reductase inhibitor

statin

HMG-CoA Reductase Inhibitor

Statin

Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors

HMG-CoA reductase inhibitor

Definitions

Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1655

ALT_DEFINITION

Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer.

CHEBI_ID

CHEBI:35664

code

C1655

DEFINITION

Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.

FULL_SYN

hydroxymethylglutaryl-coenzyme A reductase inhibitor

statin

HMG-CoA Reductase Inhibitor

Statin

Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors

HMG-CoA reductase inhibitor

label

HMG-CoA Reductase Inhibitor

Legacy_Concept_Name

HMG-CoA_Reductase_Inhibitor

Preferred_Name

HMG-CoA Reductase Inhibitor

prefixIRI

ncit:C1655

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0360714

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29703

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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http://purl.bioontology.org/ontology/RCD/x01R1 RCD LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0003994 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0003994 DMTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005327 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005327 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005327 DMTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/734592007 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906010926850000 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372912004 SNOMEDCT LOOM
http://www.owl-ontologies.com/OntologyXCT.owl#HMGCoAReductaseInhibitor CTX LOOM