National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Actin

Synonyms

Actin

Definitions

A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16258

code

C16258

DEFINITION

A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.

FULL_SYN

Actin

label

Actin

Legacy_Concept_Name

Actin

Preferred_Name

Actin

prefixIRI

ncit:C16258

Semantic_Type

Biologically Active Substance

Amino Acid, Peptide, or Protein

UMLS_CUI

C0001271

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16852

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.org/sig/ont/fma/fma67843 FMA LOOM
http://purl.bioontology.org/ontology/RCD/X80OU RCD LOOM
http://www.projecthalo.com/aura#Actin AURA LOOM
http://id.loc.gov/authorities/subjects/sh85000687 FAST-TOPICAL LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0001271 OCHV LOOM
http://uri.neuinfo.org/nif/nifstd/sao925531236 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNMI/F-62D00 SNMI LOOM
http://purl.jp/bio/4/id/200906040389792010 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/46583003 SNOMEDCT LOOM
http://ccdb.ucsd.edu/SAO/1.2#sao925531236 SAO LOOM
http://www.semanticweb.org/ontologies/2008/8/SPO_lightweight_merged.owl#Actin SPO LOOM
http://d-nb.info/gnd/4201876-6 FAST-TOPICAL LOOM
http://purl.obolibrary.org/obo/FPLX#_Actin FPLX LOOM
http://purl.obolibrary.org/obo/BE#_Actin BE LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.obolibrary.org/obo/IMR_0000190 TXPO LOOM
http://purl.bioontology.org/ontology/LNC/LP14639-6 LOINC LOOM
http://purl.org/obo/owlapi/fma#FMA_67843 BIOMODELS LOOM
http://purl.obolibrary.org/obo/FPLX_Actin FPLX LOOM
http://purl.bioontology.org/ontology/CSP/2446-6600 CRISP LOOM
http://scai.fraunhofer.de/MSOntology#Actin MSO LOOM