National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Actin

Synonyms

Actin

Definitions

A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16258

code

C16258

DEFINITION

A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.

FULL_SYN

Actin

label

Actin

Legacy Concept Name

Actin

Preferred_Name

Actin

prefixIRI

Thesaurus:C16258

Semantic_Type

Amino Acid, Peptide, or Protein

Biologically Active Substance

UMLS_CUI

C0001271

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16852

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