loading...| Preferred Name |
Ziconotide |
|
| Synonyms |
Prialt SNX 111 SNX-111 ZICONOTIDE Ziconotide ziconotide |
|
| Definitions |
A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1475 |
|
| ALT_DEFINITION |
A drug used in the treatment of chronic pain. |
|
| CAS_Registry |
107452-89-1 |
|
| Chemical_Formula |
C102H172N36O32S7 |
|
| code |
C1475 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain. |
|
| FDA_UNII_Code |
7I64C51O16 |
|
| FULL_SYN |
Prialt SNX 111 SNX-111 ZICONOTIDE Ziconotide ziconotide |
|
| Has_Salt_Form | ||
| label |
Ziconotide |
|
| Legacy Concept Name |
Ziconotide |
|
| NCI_Drug_Dictionary_ID |
42866 |
|
| PDQ_Closed_Trial_Search_ID |
42866 |
|
| PDQ_Open_Trial_Search_ID |
42866 |
|
| Preferred_Name |
Ziconotide |
|
| prefixIRI |
Thesaurus:C1475 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0211011 |
|
| subClassOf |