National Cancer Institute Thesaurus

Last uploaded: September 30, 2019
Preferred Name

Cyclooxygenase Inhibitor

Synonyms

Cyclooxygenase Inhibitor

Clyclooxygenases Inhibitor

COX inhibitor

Prostaglandin G/H Synthase Inhibitor

cyclooxygenase inhibitor

COX Inhibitor

Definitions

Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1323

ALT_DEFINITION

A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. COX inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

CHEBI_ID

CHEBI:35544

code

C1323

DEFINITION

Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.

FULL_SYN

Cyclooxygenase Inhibitor

Clyclooxygenases Inhibitor

COX inhibitor

Prostaglandin G/H Synthase Inhibitor

cyclooxygenase inhibitor

COX Inhibitor

label

Cyclooxygenase Inhibitor

Legacy_Concept_Name

Cyclooxygenase_Inhibitor

Preferred_Name

Cyclooxygenase Inhibitor

prefixIRI

ncit:C1323

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0085387

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C257

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http://purl.obolibrary.org/obo/CHEBI_35544 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_35544 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_35544 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_35544 DINTO LOOM
http://purl.bioontology.org/ontology/CSP/5005-0005 CRISP LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/782375001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/782376000 SNOMEDCT LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#cyclooxygenase_inhibitor SDO LOOM