Preferred Name |
Venlafaxine |
|
Synonyms |
venlafaxine Venlafaxine VENLAFAXINE |
|
Definitions |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1278 |
|
Accepted_Therapeutic_Use_For |
Anxiety; Depression |
|
ALT_DEFINITION |
An antidepressant drug that is being evaluated for the treatment of hot flashes in women who have breast cancer. |
|
CAS_Registry |
93413-69-5 |
|
CHEBI_ID |
CHEBI:9943 |
|
Chemical_Formula |
C17H27NO2 |
|
code |
C1278 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) |
|
Display_Name |
Venlafaxine |
|
FDA_UNII_Code |
GRZ5RCB1QG |
|
FULL_SYN |
venlafaxine Venlafaxine VENLAFAXINE |
|
Has_Salt_Form | ||
label |
Venlafaxine |
|
Legacy Concept Name |
Venlafaxine |
|
NCI_Drug_Dictionary_ID |
43238 |
|
PDQ_Closed_Trial_Search_ID |
43238 |
|
PDQ_Open_Trial_Search_ID |
43238 |
|
Preferred_Name |
Venlafaxine |
|
prefixIRI |
Thesaurus:C1278 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0078569 |
|
subClassOf |