National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Jump to:
loading...
Preferred Name

Doxycycline Hyclate Injection
Synonyms

Doxycycline Hyclate Injection
Definitions

An injectable formulation composed of the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic, with antimicrobial activity. Upon injection, doxycycline reversibly binds to the bacterial 30S ribosomal subunit, and blocks the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of bacterial protein synthesis and abrogates bacterial infections.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C125186
code

C125186
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424
DEFINITION

An injectable formulation composed of the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic, with antimicrobial activity. Upon injection, doxycycline reversibly binds to the bacterial 30S ribosomal subunit, and blocks the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of bacterial protein synthesis and abrogates bacterial infections.
FULL_SYN

Doxycycline Hyclate Injection
label

Doxycycline Hyclate Injection
NCI_Drug_Dictionary_ID

777732
NCI_META_CUI

CL504005
PDQ_Closed_Trial_Search_ID

777732
PDQ_Open_Trial_Search_ID

777732
Preferred_Name

Doxycycline Hyclate Injection
prefixIRI

Thesaurus:C125186
Semantic_Type

Pharmacologic Substance
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1595
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display