loading...| Preferred Name |
5-Hydroxylysine |
|
| Synonyms |
5-Hydroxy-Lysine (2S,5R)-5-Hydroxylysine L-Hydroxylysine Hydroxylysine HYDROXYLYSINE (2S,5R)-2,6-Diamino-5-Hydroxyhexanoic Acid (2S,5R)-2,6-Diamino-5-Hydroxyhexanoate Erythro-5-Hydroxy-L-Lysine Delta-Hydroxylysine L-Delta-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproate Hydroxy-Lysine 5-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproic Acid |
|
| Definitions |
A hydroxylated amino acid derivative of lysine that arises from post-translational modification. Lysine is converted into 5-hydroxylysine by lysyl hydroxylase, an oxoenzyme that catalyzes the hydroxylation of carbon-5 in lysyl residues found in proteins or peptides. Hydroxylysine residues are required for the formation and stability of triple helical collagen fibrils. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118878 |
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| CAS_Registry |
1190-94-9 |
|
| code |
C118878 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
A hydroxylated amino acid derivative of lysine that arises from post-translational modification. Lysine is converted into 5-hydroxylysine by lysyl hydroxylase, an oxoenzyme that catalyzes the hydroxylation of carbon-5 in lysyl residues found in proteins or peptides. Hydroxylysine residues are required for the formation and stability of triple helical collagen fibrils. |
|
| Display_Name |
5-Hydroxylysine |
|
| FDA_UNII_Code |
2GQB349IUB |
|
| FULL_SYN |
5-Hydroxy-Lysine (2S,5R)-5-Hydroxylysine L-Hydroxylysine Hydroxylysine HYDROXYLYSINE (2S,5R)-2,6-Diamino-5-Hydroxyhexanoic Acid (2S,5R)-2,6-Diamino-5-Hydroxyhexanoate Erythro-5-Hydroxy-L-Lysine Delta-Hydroxylysine L-Delta-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproate Hydroxy-Lysine 5-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproic Acid |
|
| label |
5-Hydroxylysine |
|
| Preferred_Name |
5-Hydroxylysine |
|
| prefixIRI |
Thesaurus:C118878 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| UMLS_CUI |
C4048291 |
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| subClassOf |