National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Sarcosine

Synonyms

(Methylamino)Ethanoic Acid

N-Methylaminoacetic Acid

Acetic Acid, (Methylamino)-

Glycine, N-Methyl-

Methylglycine

N-Methylglycine

Sarcosinic Acid

(Methylamino)Acetic Acid

SARCOSINE

Sarcosine

Definitions

An amino acid that is an intermediate and byproduct in glycine synthesis and degradation with potential anti-depressant and anti-schizophrenic activities. Sarcosine is a product of dietary consumption of choline and creatine and is rapidly converted into glycine. Oral administration of sarcosine with certain antipsychotics may cause increased glycine concentration in the brain, which may lead to increased NMDA receptor activation and a reduction in symptoms.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113501

CAS_Registry

107-97-1

CHEBI_ID

CHEBI:15611

code

C113501

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

An amino acid that is an intermediate and byproduct in glycine synthesis and degradation with potential anti-depressant and anti-schizophrenic activities. Sarcosine is a product of dietary consumption of choline and creatine and is rapidly converted into glycine. Oral administration of sarcosine with certain antipsychotics may cause increased glycine concentration in the brain, which may lead to increased NMDA receptor activation and a reduction in symptoms.

Display_Name

Sarcosine

FDA_UNII_Code

Z711V88R5F

FULL_SYN

(Methylamino)Ethanoic Acid

N-Methylaminoacetic Acid

Acetic Acid, (Methylamino)-

Glycine, N-Methyl-

Methylglycine

N-Methylglycine

Sarcosinic Acid

(Methylamino)Acetic Acid

SARCOSINE

Sarcosine

label

Sarcosine

Preferred_Name

Sarcosine

prefixIRI

Thesaurus:C113501

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0036228

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C231

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_15611 OBA LOOM
http://purl.obolibrary.org/obo/UPa_UPC00213 UPA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.481.700.374 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D012521 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/88546006 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012521 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP15859-9 LOINC LOOM
https://go.drugbank.com/drugs/DB12519 MDM LOOM
http://purl.bioontology.org/ontology/NDDF/011011 NDDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021316 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/MESH_D012521 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004108 LOINC LOOM
http://purl.bioontology.org/ontology/SNMI/F-64440 SNMI LOOM
http://purl.obolibrary.org/obo/NCIT_C113501 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0013424 OMIT LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 ENVO LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 FNS-H LOOM
http://purl.obolibrary.org/obo/CHEBI_15611 NMDCO LOOM
http://purl.bioontology.org/ontology/CSP/0124-3132 CRISP LOOM
http://stirdf.jst.go.jp/id/200907027067608610 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11053 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/1362906 RXNORM LOOM
http://purl.jp/bio/4/id/200906068442841381 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0036228 OCHV LOOM