Neuro Behavior Ontology

Last uploaded: May 11, 2018
Preferred Name

ketotifen

Synonyms

ketotifenum

ketotifeno

4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

ketotifen

10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one

ketotifene

Definitions

An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

ID

http://purl.obolibrary.org/obo/CHEBI_92511

charge

0

database_cross_reference

LINCS:LSM-2637

Wikipedia:Ketotifen

HMDB:HMDB0015056

DrugBank:DB00920

Drug_Central:1530

CAS:34580-13-7

KEGG:D08105

Patent:DE2111071

Patent:US3682930

definition

An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

formula

C19H19NOS

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_49167

has_exact_synonym

4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

has_obo_namespace

chebi_ontology

has_related_synonym

ketotifenum

ketotifeno

ketotifen

10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one

ketotifene

id

CHEBI:92511

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3

inchikey

ZCVMWBYGMWKGHF-UHFFFAOYSA-N

is conjugate base of

http://purl.obolibrary.org/obo/CHEBI_140417

label

ketotifen

mass

309.427

monoisotopicmass

309.119

notation

CHEBI:92511

prefixIRI

CHEBI:92511

prefLabel

ketotifen

smiles

CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_26151

http://purl.obolibrary.org/obo/CHEBI_3992

http://purl.obolibrary.org/obo/CHEBI_50996

http://purl.obolibrary.org/obo/CHEBI_78840

http://purl.obolibrary.org/obo/CHEBI_38106

http://purl.obolibrary.org/obo/CHEBI_26979

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http://purl.jp/bio/4/id/200906066742697174 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/6146 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D007665 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.370 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.778.370 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4021170 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/003742 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372642003 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Ketotifen GALEN LOOM
http://childhealthservicemodels.eu/asthma#MOCHA-Asthma_000118 AO LOOM
http://purl.obolibrary.org/obo/dinto_DB00920 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.903.370 RH-MESH LOOM
http://d-nb.info/gnd/4163678-8 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RCD/x02LJ RCD LOOM
http://www.drugbank.ca/drugs/DB00920 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/354038002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148619 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007665 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00017034 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00017034 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_92511 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_92511 CHEBI SAME_URI
http://purl.bioontology.org/ontology/UATC/S01GX08 ATC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61799 NCIT LOOM
http://purl.bioontology.org/ontology/UATC/R06AX17 ATC LOOM