Neuro Behavior Ontology

Last uploaded: May 11, 2018
Preferred Name

ramipril

Synonyms

(2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

Ramiprilum

ramipril

Altace (TN)

Tritace

(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid

Ramipril

Definitions

A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.

ID

http://purl.obolibrary.org/obo/CHEBI_8774

charge

0

database_cross_reference

KEGG:D00421

PMID:16144510

Reaxys:4214464

PMID:24397981

PMID:24435506

PMID:17004100

PMID:11095026

PMID:24090393

Drug_Central:2356

PMID:12768220

CAS:87333-19-5

PMID:24048485

PMID:17903031

PMID:24509355

Beilstein:4214464

PMID:16734081

PMID:23713675

PMID:24452090

PMID:22799880

PMID:23747952

HMDB:HMDB0014324

PMID:24191305

PMID:17192135

PMID:11575208

PMID:15110900

PMID:23951921

PMID:23842829

Wikipedia:Ramipril

LINCS:LSM-5950

DrugBank:DB00178

PMID:17496463

PMID:23557551

PMID:20122169

PMID:12076194

PMID:23842688

definition

A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.

formula

C23H32N2O5

has role

http://purl.obolibrary.org/obo/CHEBI_77496

http://purl.obolibrary.org/obo/CHEBI_50266

http://purl.obolibrary.org/obo/CHEBI_50664

http://purl.obolibrary.org/obo/CHEBI_35457

http://purl.obolibrary.org/obo/CHEBI_77307

has_exact_synonym

(2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

Ramipril

has_obo_namespace

chebi_ontology

has_related_synonym

Ramiprilum

ramipril

Altace (TN)

Tritace

(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid

id

CHEBI:8774

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1

inchikey

HDACQVRGBOVJII-JBDAPHQKSA-N

label

ramipril

mass

416.51060

monoisotopicmass

416.231

notation

CHEBI:8774

prefixIRI

CHEBI:8774

prefLabel

ramipril

smiles

CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_23990

http://purl.obolibrary.org/obo/CHEBI_46761

http://purl.obolibrary.org/obo/CHEBI_38295

http://purl.obolibrary.org/obo/CHEBI_38296

http://purl.obolibrary.org/obo/CHEBI_36244

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Delete Mapping To Ontology Source
http://purl.jp/bio/4/id/200906061080094006 IOBC LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#ramipril SDO LOOM
http://purl.bioontology.org/ontology/MESH/D017257 MESH LOOM
http://purl.bioontology.org/ontology/UATC/C09AA05 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8774 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8774 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8774 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8774 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8774 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8774 NIFSTD SAME_URI
https://bioportal.bioontology.org/ontologies/FTDM.owl#ramipril FASTO LOOM
http://purl.bioontology.org/ontology/LNC/LP171634-1 LOINC LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000548 XCO LOOM
http://www.drugbank.ca/drugs/DB00178 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386872004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4019562 VANDF LOOM
http://bmi.utah.edu/ontologies/hfontology/C0072973 HFO LOOM
http://purl.bioontology.org/ontology/RXNORM/35296 RXNORM LOOM
http://purl.bioontology.org/ontology/RXNORM/35296 NLMVS LOOM
http://www.semanticweb.org/ontologies/STO.owl#f755b006_ddd3_4b8a_a155_5e3d704d69be CVAO LOOM
http://www.semanticweb.org/ontologies/STO.owl#f755b006_ddd3_4b8a_a155_5e3d704d69be STO-DRAFT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.750 RH-MESH LOOM
http://scai.fraunhofer.de/AlzheimerOntology#ramipril ADO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29411 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29411 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29411 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29411 NCIT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147662 ODAE LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108564000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/003585 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017257 RH-MESH LOOM
http://d-nb.info/gnd/4301017-9 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RCD/bi6.. RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147662 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Ramipril GALEN LOOM