loading...| Preferred Name |
dacarbazine |
| Synonyms |
Di-me-triazenoimidazolecarboxamide Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)- 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide dacarbazine NSC 45388 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide NCI-C04717 HSDB 3219 deticene 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide Dtic-Dome (TN) dacarbazina 5-(3,3-dimethyltriazeno)imidazole-4-carboxamide 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide DTIC 5-(dimethyltriazeno)imidazole-4-carboxamide 4-(dimethyltriazeno)imidazole-5-carboxamide DIC ICDMT NSC-45388 dacarbazinum 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide |
| Definitions |
A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma. |
| ID |
http://purl.obolibrary.org/obo/CHEBI_4305 |
| charge |
0 |
| database_cross_reference |
PMID:10751609 PMID:15010317 PMID:29296081 PMID:29076951 Reaxys:521487 PMID:20082117 PMID:29184162 PMID:26940170 PMID:29305638 KEGG:D00288 PMID:29287706 Wikipedia:Dacarbazine PMID:12195827 PMID:28250333 Beilstein:521487 PMID:28387914 PMID:28419676 PMID:23029050 KEGG:C06936 CAS:4342-03-4 DrugBank:DB00851 PMID:21654834 Drug_Central:773 PMID:21471822 PMID:23318786 PMID:28096700 PMID:29344241 PMID:11318431 |
| definition |
A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma. |
| formula |
C6H10N6O |
| has role |
http://purl.obolibrary.org/obo/CHEBI_50266 http://purl.obolibrary.org/obo/CHEBI_35610 |
| has_exact_synonym |
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide |
| has_obo_namespace |
chebi_ontology |
| has_related_synonym |
Di-me-triazenoimidazolecarboxamide Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)- dacarbazine NSC 45388 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide NCI-C04717 HSDB 3219 deticene 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide Dtic-Dome (TN) dacarbazina 5-(3,3-dimethyltriazeno)imidazole-4-carboxamide 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide DTIC 5-(dimethyltriazeno)imidazole-4-carboxamide 4-(dimethyltriazeno)imidazole-5-carboxamide DIC ICDMT NSC-45388 dacarbazinum 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide |
| id |
CHEBI:4305 |
| in_subset | |
| inchi |
InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9) |
| inchikey |
FDKXTQMXEQVLRF-UHFFFAOYSA-N |
| label |
dacarbazine |
| mass |
182.183 |
| monoisotopicmass |
182.092 |
| notation |
CHEBI:4305 |
| prefixIRI |
CHEBI:4305 |
| prefLabel |
dacarbazine |
| smiles |
C=1NC(=C(N1)C(=O)N)N=NN(C)C |
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_72573 |