loading...| Preferred Name |
Alzheimer's disease |
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| Synonyms |
AD Alzheimers dementia Alzheimer disease Alzheimer disease, familial |
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| Definitions |
Xref MGI. OMIM mapping confirmed by DO. [SN]. A dementia and a tauopathy that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. |
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| ID |
http://purl.obolibrary.org/obo/DOID_10652 |
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| comment |
Xref MGI. OMIM mapping confirmed by DO. [SN]. |
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| database_cross_reference |
SNOMEDCT_2010_1_31:26929004 OMIM:104310 OMIM:615711 NCI:C38778 EFO:0000249 OMIM:611152 OMIM:502500 SNOMEDCT_2010_1_31:154998003 OMIM:604154 OMIM:607116 OMIM:611154 OMIM:605526 OMIM:609790 MSH:D000544 NCI:C2866 OMIM:300756 OMIM:606889 OMIM:602096 ICD9CM:331.0 MSH:C536597 OMIM:615080 SNOMEDCT_2010_1_31:192164001 UMLS_CUI:C0002395 OMIM:611073 OMIM:608907 OMIM:615590 SNOMEDCT_2010_1_31:267688001 KEGG:05010 OMIM:607822 OMIM:606187 OMIM:104300 OMIM:609636 ICD10CM:G30 SNOMEDCT_2010_1_31:192160005 OMIM:611155 SNOMEDCT_2010_1_31:73768007 |
|
| definition |
A dementia and a tauopathy that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability. |
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| has exact synonym |
AD Alzheimers dementia Alzheimer disease |
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| has related synonym |
Alzheimer disease, familial |
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| has_obo_namespace |
disease_ontology |
|
| id |
DOID:10652 |
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| in_subset | ||
| label |
Alzheimer's disease |
|
| notation |
DOID:10652 |
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| prefLabel |
Alzheimer's disease |
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| subClassOf |