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Last uploaded: January 31, 2024

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Preferred Name	Lopinavir
Synonyms	ABT-378
Definitions	An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
ID	http://purl.bioontology.org/ontology/MESH/D061466
altLabel	ABT-378 ABT378 N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide A 157378.0 A157378.0 ABT 378 A-157378.0
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0674432 C1110556 C0674433
DC	1
definition	An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
DX	20120101
HN	2012
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	2494G1JF75 0
isa	http://purl.bioontology.org/ontology/MESH/D065692 http://purl.bioontology.org/ontology/MESH/D017320
Machine permutation	2012; LOPNAVIR was indexed under PYRIMIDINONES 2000-2011
Mapped from	http://purl.bioontology.org/ontology/MESH/C558899
MDA	20110627
MMR	20160701
MN	D03.383.742.698.553
notation	D061466
PA	D065692 D017320
prefLabel	Lopinavir
TERMUI	T792536 T319890 T319891 T428463 T428461
TH	NLM (2000) NLM (2012) FDA SRS (2014) USAN (19XX) INN (19XX) NLM (1998)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D011744

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/VANDF/4021228	VANDF	CUI
http://purl.bioontology.org/ontology/MSHFRE/D061466	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D061466	MSHFRE	CUI
http://purl.bioontology.org/ontology/LNC/LP28756-2	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148672	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/008874	NDDF	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/129475001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/129475001	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387067003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/387067003	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/MTHU014678	LOINC	CUI
http://purl.bioontology.org/ontology/MSHFRE/D061466	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179581	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/5006-0022	CRISP	CUI
http://purl.bioontology.org/ontology/RXNORM/195088	RXNORM	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000540623	PDQ	CUI
http://purl.obolibrary.org/obo/XCO_0001172	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	CHEBI	LOOM
http://purl.bioontology.org/ontology/VANDF/4021228	VANDF	LOOM
http://purl.bioontology.org/ontology/LNC/LP28756-2	LOINC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148672	NDFRT	LOOM
http://purl.bioontology.org/ontology/NDDF/008874	NDDF	LOOM
https://go.drugbank.com/drugs/DB01601	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D061466	RH-MESH	LOOM
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001129	HUPSON	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148672	INBANCIDO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148672	CIDO	LOOM
http://purl.obolibrary.org/obo/dinto_DB01601	DINTO	LOOM
http://purl.obolibrary.org/obo/NCIT_C2095	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#42574	OCHV	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0674432	OCHV	LOOM
http://purl.obolibrary.org/obo/MESH_D061466	BERO	LOOM
http://purl.obolibrary.org/obo/DRON_00016421	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/DRON_00016421	CIDO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387067003	SNOMEDCT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2095	NCIT	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_31781	CIDO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018468	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/OMIT_0027975	OMIT	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU014678	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.698.553	RH-MESH	LOOM
http://purl.bioontology.org/ontology/CSP/5006-0022	CRISP	LOOM
http://purl.bioontology.org/ontology/RXNORM/195088	RXNORM	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000540623	PDQ	LOOM