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Last uploaded: January 31, 2024

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Preferred Name	Ephrin-A1
Synonyms	Ligand, Eck
Definitions	An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
ID	http://purl.bioontology.org/ontology/MESH/D036382
altLabel	Ligand, Eck LERK-1 Protein B61 Secreted Protein, Endothelium Endothelium Secreted Protein B61 Ephrin A1 EPLG1 LERK 1 Protein Eck RPTK Ligand RPTK Ligand, Eck Epl1 Protein Eck Ligand EFNA1
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0246321
DC	1
definition	An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
DX	20030101
HN	2003; use EPHRIN-A1 (NM) 1990-2002
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Machine permutation	2003; ENDOTHELIUM SECRETED PROTEIN B61 (now Ephrin-A1) was indexed under PROTEINS 1990-2002,
Mapped from	http://purl.bioontology.org/ontology/MESH/C489246 http://purl.bioontology.org/ontology/MESH/C000632605
MDA	20020702
MMR	20230316
MN	D09.400.430.890.448.300 D12.776.543.287.100 D12.776.543.484.500.300 D12.644.276.500.100 D12.776.543.550.418.300 D12.776.395.550.448.300 D12.776.467.500.100 D23.529.500.100
notation	D036382
prefLabel	Ephrin-A1
TERMUI	T211713 T001104165 T211711 T211717 T211715 T211712 T211716 T211710 T211714
TH	NLM (2022) NLM (2003)
tui	T116 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D036342 http://purl.bioontology.org/ontology/MESH/D058851

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D036382	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170960	NDFRT	CUI
http://purl.obolibrary.org/obo/PR_000006916	EFO	LOOM
http://purl.obolibrary.org/obo/PR_000006916	OBA	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021625	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/OMIM/191164	OMIM	LOOM
http://www.drugtargetontology.org/dto/DTO_03100123	DTO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D036382	RH-MESH	LOOM
http://id.nlm.nih.gov/mesh/D036382	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.543.484.500.300	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.543.287.100	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.529.500.100	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.543.550.418.300	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0022699	OMIT	LOOM
http://purl.jp/bio/4/id/200906071878484216	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D036382	BERO	LOOM
http://purl.obolibrary.org/obo/PR_000006916	PR	LOOM
http://purl.obolibrary.org/obo/PR_000006916	NIFSTD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.276.500.100	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.395.550.448.300	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.500.100	RH-MESH	LOOM