Medical Subject Headings

Last uploaded: January 31, 2024
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Preferred Name

Genistein
Synonyms

Genestein
Definitions

An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
ID

http://purl.bioontology.org/ontology/MESH/D019833
altLabel

Genestein
AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui

C0061202
DC

1
definition

An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
DX

19980101
HN

98; use GENISTEIN (NM) 1980-97
Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB

DH2M523P0H
isa

http://purl.bioontology.org/ontology/MESH/D048789

http://purl.bioontology.org/ontology/MESH/D047428

http://purl.bioontology.org/ontology/MESH/D016588
Machine permutation

98; GENISTEIN was indexed under ISOFLAVONES 1976-97
Mapped from

http://purl.bioontology.org/ontology/MESH/C000720701

http://purl.bioontology.org/ontology/MESH/C462199

http://purl.bioontology.org/ontology/MESH/C578980

http://purl.bioontology.org/ontology/MESH/C067397

http://purl.bioontology.org/ontology/MESH/C508644

http://purl.bioontology.org/ontology/MESH/C476210

http://purl.bioontology.org/ontology/MESH/C482258

http://purl.bioontology.org/ontology/MESH/C482259

http://purl.bioontology.org/ontology/MESH/C000721649

http://purl.bioontology.org/ontology/MESH/C568064

http://purl.bioontology.org/ontology/MESH/C473311

http://purl.bioontology.org/ontology/MESH/C551846

http://purl.bioontology.org/ontology/MESH/C551847

http://purl.bioontology.org/ontology/MESH/C579741

http://purl.bioontology.org/ontology/MESH/C544968

http://purl.bioontology.org/ontology/MESH/C541079

http://purl.bioontology.org/ontology/MESH/C401294

http://purl.bioontology.org/ontology/MESH/C562013

http://purl.bioontology.org/ontology/MESH/C562014

http://purl.bioontology.org/ontology/MESH/C004541

http://purl.bioontology.org/ontology/MESH/C493505

http://purl.bioontology.org/ontology/MESH/C000631249

http://purl.bioontology.org/ontology/MESH/C523358

http://purl.bioontology.org/ontology/MESH/C523359

http://purl.bioontology.org/ontology/MESH/C415443

http://purl.bioontology.org/ontology/MESH/C425945
MDA

19970620
MMR

20160531
MN

D03.633.100.150.266.450.400.375

D03.383.663.283.266.450.400.375
notation

D019833
PA

D047428

D016588

D048789
prefLabel

Genistein
RR

446-72-0 (Genistein)
TERMUI

T059011

T059010
TH

FDA SRS (2014)

NLM (1998)
tui

T109

T123

T121
subClassOf

http://purl.bioontology.org/ontology/MESH/D007529
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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/PDQ/CDR0000043214 PDQ CUI
http://purl.bioontology.org/ontology/NDDF/012223 NDDF CUI
http://purl.bioontology.org/ontology/MSHFRE/D019833 MSHFRE CUI
http://purl.bioontology.org/ontology/LNC/LP14121-5 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU011484 LOINC CUI
http://purl.bioontology.org/ontology/RXNORM/25696 RXNORM CUI
http://purl.bioontology.org/ontology/CSP/4006-0042 CRISP CUI
http://purl.bioontology.org/ontology/NDFRT/N0000167031 NDFRT CUI
http://purl.obolibrary.org/obo/CHEBI_28088 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 CDNO LOOM
http://purl.jp/bio/4/id/200906051354607808 IOBC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043214 PDQ LOOM
http://purl.obolibrary.org/obo/MESH_D019833 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14087 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0061202 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 FOBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28088 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.150.266.450.400.375 RH-MESH LOOM
http://www.bioontology.org/pma.owl#PMA_1313 PMA LOOM
http://purl.bioontology.org/ontology/NDDF/012223 NDDF LOOM
http://id.nlm.nih.gov/mesh/D019833 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017632 PMAPP-PMO LOOM
http://www.drugbank.ca/drugs/DB01645 FTC LOOM
http://purl.bioontology.org/ontology/LNC/LP14121-5 LOINC LOOM
http://purl.obolibrary.org/obo/OMIT_0019810 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.830.219.266.450.400.375 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU011484 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/25696 RXNORM LOOM
https://www.fns-cloud.eu/foodComponents/FNS_H_0000003306 FNS-H LOOM
http://purl.obolibrary.org/obo/ARO_3007357 ARO LOOM
http://purl.obolibrary.org/obo/NCIT_C1113 BERO LOOM
http://purl.bioontology.org/ontology/CSP/4006-0042 CRISP LOOM
https://go.drugbank.com/drugs/DB01645 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1113 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019833 RH-MESH LOOM