Medical Subject Headings

Last uploaded: April 29, 2019
Preferred Name

Multiple System Atrophy

Synonyms

Atrophies, Multisystem

Definitions

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)

ID

http://purl.bioontology.org/ontology/MESH/D019578

altLabel

Atrophies, Multisystem

Multiple System Atrophy Syndrome

Multisystem Atrophy

Atrophy, Multisystem

Multisystem Atrophies

Multisystemic Atrophies

Atrophy, Multiple System

Multiple System Atrophies

Multisystemic Atrophy

Atrophy, Multisystemic

Atrophies, Multisystemic

AN

a specific neurodegenerative syndrome complex; not for atrophy in other systems

AQL

BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI

cui

C0393571

DC

1

definition

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)

DX

19980101

FX

D012791

D009849

HN

1998

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000401

http://purl.bioontology.org/ontology/MESH/Q000150

http://purl.bioontology.org/ontology/MESH/Q000188

http://purl.bioontology.org/ontology/MESH/Q000517

http://purl.bioontology.org/ontology/MESH/Q000201

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000503

http://purl.bioontology.org/ontology/MESH/Q000453

http://purl.bioontology.org/ontology/MESH/Q000208

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000821

http://purl.bioontology.org/ontology/MESH/Q000382

http://purl.bioontology.org/ontology/MESH/Q000601

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000523

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000662

http://purl.bioontology.org/ontology/MESH/Q000151

http://purl.bioontology.org/ontology/MESH/Q000628

http://purl.bioontology.org/ontology/MESH/Q000196

http://purl.bioontology.org/ontology/MESH/Q000534

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000532

http://purl.bioontology.org/ontology/MESH/Q000139

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000175

http://purl.bioontology.org/ontology/MESH/Q000000981

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000473

http://purl.bioontology.org/ontology/MESH/Q000451

http://purl.bioontology.org/ontology/MESH/Q000209

http://purl.bioontology.org/ontology/MESH/Q000178

http://purl.bioontology.org/ontology/MESH/Q000469

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D012791

http://purl.bioontology.org/ontology/MESH/D009849

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D006816

http://purl.bioontology.org/ontology/MESH/D000070627

http://purl.bioontology.org/ontology/MESH/D052879

http://purl.bioontology.org/ontology/MESH/D020821

http://purl.bioontology.org/ontology/MESH/D013494

http://purl.bioontology.org/ontology/MESH/D020144

http://purl.bioontology.org/ontology/MESH/D020361

http://purl.bioontology.org/ontology/MESH/D004402

http://purl.bioontology.org/ontology/MESH/D020271

http://purl.bioontology.org/ontology/MESH/D017204

http://purl.bioontology.org/ontology/MESH/D024801

http://purl.bioontology.org/ontology/MESH/D009459

http://purl.bioontology.org/ontology/MESH/D020820

http://purl.bioontology.org/ontology/MESH/D006527

http://purl.bioontology.org/ontology/MESH/D017109

http://purl.bioontology.org/ontology/MESH/D020329

http://purl.bioontology.org/ontology/MESH/D006211

http://purl.bioontology.org/ontology/MESH/D005879

http://purl.bioontology.org/ontology/MESH/D020150

http://purl.bioontology.org/ontology/MESH/D020734

http://purl.bioontology.org/ontology/MESH/D054970

http://purl.bioontology.org/ontology/MESH/D013981

http://purl.bioontology.org/ontology/MESH/D010300

http://purl.bioontology.org/ontology/MESH/D017096

http://purl.bioontology.org/ontology/MESH/D016262

http://purl.bioontology.org/ontology/MESH/D054971

http://purl.bioontology.org/ontology/MESH/D020961

http://purl.bioontology.org/ontology/MESH/D016472

http://purl.bioontology.org/ontology/MESH/D008538

http://purl.bioontology.org/ontology/MESH/D004422

http://purl.bioontology.org/ontology/MESH/D057177

Machine permutation

1998

Mapped from

http://purl.bioontology.org/ontology/MESH/C537381

MDA

19970620

MMR

20130708

MN

C10.177.575.550

C10.228.662.550

C10.574.625

C10.228.140.079.612

notation

D019578

prefLabel

Multiple System Atrophy

TERMUI

T364305

T364299

T364298

T058282

TH

NLM (1998)

NLM (2000)

ORD (2010)

OMIM (2013)

GHR (2014)

tui

T046

subClassOf

http://purl.bioontology.org/ontology/MESH/D001480

http://purl.bioontology.org/ontology/MESH/D009069

http://purl.bioontology.org/ontology/MESH/D019636

http://purl.bioontology.org/ontology/MESH/D054969

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http://purl.obolibrary.org/obo/ND_0000129 NDDO LOOM
http://purl.obolibrary.org/obo/ND_0000129 NDDO LOOM
http://purl.bioontology.org/ontology/RCTV2/F174.00 RCTV2 LOOM
http://www.orpha.net/ORDO/Orphanet_102 ORDO LOOM
http://www.orpha.net/ORDO/Orphanet_102 ORDO LOOM
http://www.orpha.net/ORDO/Orphanet_102 HORD LOOM
http://www.orpha.net/ORDO/Orphanet_102 ORDO LOOM
http://bioontology.org/projects/ontologies/birnlex#birnlex_12573 BIRNLEX LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0393571 MEDLINEPLUS CUI
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0393571 MEDLINEPLUS LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_12573 NIFDYS LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_12573 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.177.575.550 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000003942 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/230297002 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/230297002 SNOMEDCT LOOM
http://www.semanticweb.org/ontologies/2011/1/Ontology1296772722296.owl#Multiple_system_atrophy PDON LOOM
http://purl.org/obo/owl/DOID#DOID_4752 HUPSON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.228.140.079.612 RH-MESH LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Multiple_System_atrophy ADO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Multiple_System_Atrophy CSEO LOOM
http://purl.bioontology.org/ontology/RCD/X003n RCD CUI
http://purl.bioontology.org/ontology/RCD/X003n RCD LOOM
http://radlex.org/RID/RID5158 RADLEX LOOM
http://purl.obolibrary.org/obo/DOID_4752 BAO LOOM
http://purl.obolibrary.org/obo/DOID_4752 DTO LOOM
http://purl.obolibrary.org/obo/DOID_4752 BAO LOOM
http://purl.obolibrary.org/obo/DOID_4752 DOID LOOM
http://purl.obolibrary.org/obo/DOID_4752 NIFSTD LOOM
http://www.limics.org/hrdo/rdfns#pat_id_8744 HRDO LOOM
http://purl.obolibrary.org/obo/MONDO_0007803 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0007803 MONDO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10064060 MEDDRA CUI
http://purl.bioontology.org/ontology/MEDDRA/10064060 MEDDRA LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 CCONT LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1001050 EFO LOOM
http://purl.jp/bio/4/id/200906062420544911 IOBC LOOM
http://purl.jp/bio/4/id/200906062420544911 IOBC LOOM
http://purl.jp/bio/4/id/200906062420544911 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.228.662.550 RH-MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Multiple_System_Atrophy APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Multiple_System_Atrophy APAONTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.574.625 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019578 RH-MESH LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_4752 NATPRO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84909 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84909 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84909 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84909 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84909 NCIT LOOM