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Last uploaded: January 31, 2024

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Preferred Name	Paclitaxel
Synonyms	Taxol, Bris Taxol A
Definitions	A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
ID	http://purl.bioontology.org/ontology/MESH/D017239
altLabel	Taxol, Bris Paxene Bris Taxol 7-epi-Taxol Onxol Anzatax Praxel NSC-125973 7 epi Taxol Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR,betaS),11alpha,1-2alpha,12aalpha,12balpha))- NSC125973 NSC 125973 Paclitaxel, (4 alpha)-Isomer Taxol Taxol A
AQL	AA AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0886723 C0678133 C0729159 C0099800 C0144576 C1518839 C0729158 C1518836 C0939420
DC	1
definition	A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
DX	19930101
HN	95; was TAXOL 1993-94; was TAXOL A (NM) 1977-92
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	P88XT4IS4D 105454-04-4 0
isa	http://purl.bioontology.org/ontology/MESH/D000972 http://purl.bioontology.org/ontology/MESH/D050257
LT	TRD
Machine permutation	95; was TAXOL 1993-94; TAXOL A was indexed under ALKALOIDS 1982-92 & TERPENES 1977-81
Mapped from	http://purl.bioontology.org/ontology/MESH/C497332 http://purl.bioontology.org/ontology/MESH/C567982 http://purl.bioontology.org/ontology/MESH/C000592762 http://purl.bioontology.org/ontology/MESH/C518515 http://purl.bioontology.org/ontology/MESH/C497149 http://purl.bioontology.org/ontology/MESH/C531859 http://purl.bioontology.org/ontology/MESH/C560640 http://purl.bioontology.org/ontology/MESH/C496493 http://purl.bioontology.org/ontology/MESH/C495179 http://purl.bioontology.org/ontology/MESH/C481188 http://purl.bioontology.org/ontology/MESH/C581525 http://purl.bioontology.org/ontology/MESH/C582518 http://purl.bioontology.org/ontology/MESH/C481001 http://purl.bioontology.org/ontology/MESH/C520255 http://purl.bioontology.org/ontology/MESH/C528070 http://purl.bioontology.org/ontology/MESH/C525213 http://purl.bioontology.org/ontology/MESH/C508480 http://purl.bioontology.org/ontology/MESH/C508481 http://purl.bioontology.org/ontology/MESH/C416023 http://purl.bioontology.org/ontology/MESH/C492673 http://purl.bioontology.org/ontology/MESH/C425385 http://purl.bioontology.org/ontology/MESH/C582620 http://purl.bioontology.org/ontology/MESH/C000625867 http://purl.bioontology.org/ontology/MESH/C511389 http://purl.bioontology.org/ontology/MESH/C476718 http://purl.bioontology.org/ontology/MESH/C531111 http://purl.bioontology.org/ontology/MESH/C541324 http://purl.bioontology.org/ontology/MESH/C543033 http://purl.bioontology.org/ontology/MESH/C533913 http://purl.bioontology.org/ontology/MESH/C578609 http://purl.bioontology.org/ontology/MESH/C526531 http://purl.bioontology.org/ontology/MESH/C111043 http://purl.bioontology.org/ontology/MESH/C000708971 http://purl.bioontology.org/ontology/MESH/C485231 http://purl.bioontology.org/ontology/MESH/C495226 http://purl.bioontology.org/ontology/MESH/C479501 http://purl.bioontology.org/ontology/MESH/C509139 http://purl.bioontology.org/ontology/MESH/C534103 http://purl.bioontology.org/ontology/MESH/C522040 http://purl.bioontology.org/ontology/MESH/C000624440 http://purl.bioontology.org/ontology/MESH/C000610507 http://purl.bioontology.org/ontology/MESH/C533210 http://purl.bioontology.org/ontology/MESH/C585584 http://purl.bioontology.org/ontology/MESH/C485024 http://purl.bioontology.org/ontology/MESH/C477186 http://purl.bioontology.org/ontology/MESH/C548171 http://purl.bioontology.org/ontology/MESH/C479518 http://purl.bioontology.org/ontology/MESH/C568100 http://purl.bioontology.org/ontology/MESH/C575004 http://purl.bioontology.org/ontology/MESH/C575005 http://purl.bioontology.org/ontology/MESH/C518962 http://purl.bioontology.org/ontology/MESH/C520232 http://purl.bioontology.org/ontology/MESH/C500671 http://purl.bioontology.org/ontology/MESH/C000610506 http://purl.bioontology.org/ontology/MESH/C508211 http://purl.bioontology.org/ontology/MESH/C508212 http://purl.bioontology.org/ontology/MESH/C532167 http://purl.bioontology.org/ontology/MESH/C540148
MDA	19991104
MMR	20141014
MN	D02.455.426.392.368.242.888.777 D02.455.849.291.850.777
notation	D017239
OL	use PACLITAXEL to search TAXOL 1993-94; use PACLITAXEL (NM) to search TAXOL A 1977-92
PA	D000972 D050257
prefLabel	Paclitaxel
RR	33069-62-4 105454-04-4 ((4 alpha)-isomer)
TERMUI	T359525 T051392 T051394 T616368 T051396 T616360 T616365 T616366 T051391 T051393 T051395
TH	NLM (1997) US MX UK NLM (1993) NL NLM (1999) NLM (1995) ES USAN (19XX) INN (19XX) DE AU FDA SRS (2015) BAN (19XX) FR
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D043823

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	CUI
http://purl.bioontology.org/ontology/SNMI/C-78320	SNMI	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039762	PDQ	CUI
http://purl.bioontology.org/ontology/MSHFRE/D017239	MSHFRE	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039762	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/x02sE	RCD	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039762	PDQ	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387374002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/67735003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/67735003	SCTSPA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D017239	MSHFRE	CUI
http://purl.bioontology.org/ontology/ATC/L01CD01	ATC	CUI
http://purl.bioontology.org/ontology/NDDF/004116	NDDF	CUI
http://purl.bioontology.org/ontology/SCTSPA/387374002	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039762	PDQ	CUI
http://purl.bioontology.org/ontology/VANDF/4020736	VANDF	CUI
http://purl.bioontology.org/ontology/RCD/h5B..	RCD	CUI
http://purl.bioontology.org/ontology/LNC/LP101036-4	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/56946	RXNORM	CUI
http://purl.bioontology.org/ontology/LNC/MTHU060612	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148314	NDFRT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007153	NDFRT	CUI
http://purl.obolibrary.org/obo/CHEBI_45863	EFO	LOOM
http://purl.obolibrary.org/obo/XCO_0000735	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	DIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_45863	ODNAE	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017239	RH-MESH	LOOM
http://www.co-ode.org/ontologies/galen#Paclitaxel	GALEN	LOOM
http://stirdf.jst.go.jp/id/200907040288876926	IOBC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78320	SNMI	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387374002	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/CSP/0093-3150	CRISP	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_45863	NPO	LOOM
https://go.drugbank.com/drugs/DB01229	MDM	LOOM
http://www.drugbank.ca/drugs/DB01229	FTC	LOOM
http://purl.obolibrary.org/obo/OMIT_0017624	OMIT	LOOM
http://www.semanticweb.org/hx-jta/ontologies/thyroid_cancer_ontology#Paclitaxel	TCO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0144576	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/L01CD01	ATC	LOOM
http://ontology.lst.tfo.upm.es/SPT/follow#Cancer_Therapy_Agent_Name_rec_met@@7	HENEGEO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148314	ODAE	LOOM
http://purl.bioontology.org/ontology/NDDF/004116	NDDF	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016747	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/NCIT_C1411	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.242.888.777	RH-MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16532	OCHV	LOOM
http://purl.obolibrary.org/obo/MESH_D017239	BERO	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039762	PDQ	LOOM
http://purl.bioontology.org/ontology/VANDF/4020736	VANDF	LOOM
http://purl.bioontology.org/ontology/RCD/h5B..	RCD	LOOM
http://neuromorpho.org/ontologies/experimentconditionH.owl#NMOOt_622	NMOBR	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411	NCIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411	ROO	LOOM
http://purl.bioontology.org/ontology/LNC/LP101036-4	LOINC	LOOM
http://purl.bioontology.org/ontology/RXNORM/56946	RXNORM	LOOM
http://ontology.lst.tfo.upm.es/BD2D/chemo#Cancer_Therapy_Agent_Name@@6	HENECON	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060612	LOINC	LOOM
http://purl.jp/bio/4/id/200906043304612581	IOBC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148314	NDFRT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.291.850.777	RH-MESH	LOOM