Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Cyclooxygenase Inhibitors
Synonyms	Prostaglandin Endoperoxide Synthase Inhibitor Inhibitor, Cyclo-Oxygenase
Definitions	Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
ID	http://purl.bioontology.org/ontology/MESH/D016861
altLabel	Prostaglandin Endoperoxide Synthase Inhibitor Antagonist, Prostaglandin Synthesis Cyclo-Oxygenase Inhibitor Inhibitors, Prostaglandin Endoperoxide Synthase Cyclo-Oxygenase Inhibitors Prostaglandin Synthase Inhibitor Antagonists, Prostaglandin Synthesis Synthesis Antagonist, Prostaglandin Cyclooxygenase Inhibitor Inhibitors, Cyclo-Oxygenase Synthase Inhibitor, Prostaglandin Prostaglandin Synthesis Antagonists Inhibitor, Cyclooxygenase Prostaglandin Synthase Inhibitors Prostaglandin Endoperoxide Synthase Inhibitors Inhibitors, Prostaglandin-Endoperoxide Synthase Inhibitor, Prostaglandin Synthase Inhibitors, Prostaglandin Synthase Cyclo Oxygenase Inhibitor Cyclo Oxygenase Inhibitors Inhibitors, Cyclo Oxygenase Inhibitors, Cyclooxygenase Prostaglandin Synthesis Antagonist Inhibitor, Cyclo-Oxygenase
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0085387
DC	1
definition	Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
DX	19920101
HN	92; PROSTAGLANDIN SYNTHESIS ANTAGONISTS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1987-94
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of isa	http://purl.bioontology.org/ontology/MESH/D000097245 http://purl.bioontology.org/ontology/MESH/C119130 http://purl.bioontology.org/ontology/MESH/C496892 http://purl.bioontology.org/ontology/MESH/C075386 http://purl.bioontology.org/ontology/MESH/C409370 http://purl.bioontology.org/ontology/MESH/D009637 http://purl.bioontology.org/ontology/MESH/C059178 http://purl.bioontology.org/ontology/MESH/C020371 http://purl.bioontology.org/ontology/MESH/C012655 http://purl.bioontology.org/ontology/MESH/D004008 http://purl.bioontology.org/ontology/MESH/C085131 http://purl.bioontology.org/ontology/MESH/C011385 http://purl.bioontology.org/ontology/MESH/D007052 http://purl.bioontology.org/ontology/MESH/D012459 http://purl.bioontology.org/ontology/MESH/C080955 http://purl.bioontology.org/ontology/MESH/C010725 http://purl.bioontology.org/ontology/MESH/D001241 http://purl.bioontology.org/ontology/MESH/C088092 http://purl.bioontology.org/ontology/MESH/D007660 http://purl.bioontology.org/ontology/MESH/C115461 http://purl.bioontology.org/ontology/MESH/D013496 http://purl.bioontology.org/ontology/MESH/C064874 http://purl.bioontology.org/ontology/MESH/D013467 http://purl.bioontology.org/ontology/MESH/C025463 http://purl.bioontology.org/ontology/MESH/C000626821 http://purl.bioontology.org/ontology/MESH/C054999 http://purl.bioontology.org/ontology/MESH/C004921 http://purl.bioontology.org/ontology/MESH/C062866 http://purl.bioontology.org/ontology/MESH/D015772 http://purl.bioontology.org/ontology/MESH/C090859 http://purl.bioontology.org/ontology/MESH/D000077431 http://purl.bioontology.org/ontology/MESH/C080200 http://purl.bioontology.org/ontology/MESH/C080201 http://purl.bioontology.org/ontology/MESH/C015429 http://purl.bioontology.org/ontology/MESH/D005279 http://purl.bioontology.org/ontology/MESH/D004061 http://purl.bioontology.org/ontology/MESH/C005696 http://purl.bioontology.org/ontology/MESH/C401741 http://purl.bioontology.org/ontology/MESH/D007216 http://purl.bioontology.org/ontology/MESH/D007213 http://purl.bioontology.org/ontology/MESH/D005480 http://purl.bioontology.org/ontology/MESH/D008528 http://purl.bioontology.org/ontology/MESH/C093700 http://purl.bioontology.org/ontology/MESH/C479680 http://purl.bioontology.org/ontology/MESH/D010894 http://purl.bioontology.org/ontology/MESH/C032801 http://purl.bioontology.org/ontology/MESH/D012980 http://purl.bioontology.org/ontology/MESH/D009288 http://purl.bioontology.org/ontology/MESH/C010395 http://purl.bioontology.org/ontology/MESH/C412806 http://purl.bioontology.org/ontology/MESH/C471996 http://purl.bioontology.org/ontology/MESH/D014046 http://purl.bioontology.org/ontology/MESH/D020910 http://purl.bioontology.org/ontology/MESH/D020911 http://purl.bioontology.org/ontology/MESH/C042986 http://purl.bioontology.org/ontology/MESH/D009544 http://purl.bioontology.org/ontology/MESH/D008469
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D011448
Machine permutation	92; PROSTAGLANDIN SYNTHESIS ANTAGONISTS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1987-94
MDA	19910718
MMR	20200527
MN	D27.505.519.389.310 D27.505.954.158.030.500 D27.505.696.663.850.014.040.500.500 D27.505.954.329.030.500
notation	D016861
OL	use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search PROSTAGLANDIN SYNTHESIS ANTAGONISTS 1987-94
prefLabel	Cyclooxygenase Inhibitors
TERMUI	T050483 T050484 T050487 T050482 T050489 T050488 T000998166 T050490 T050486 T000998168 T000998167 T000998164 T000998165 T050485
TH	NLM (1995) NLM (1992) NLM (2021)
tui	T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D000894 http://purl.bioontology.org/ontology/MESH/D004791

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D016861	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/782376000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/CSP/5005-0005	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/782376000	SCTSPA	CUI
http://purl.obolibrary.org/obo/OMIT_0017295	OMIT	LOOM
http://purl.jp/bio/4/id/200906054755570833	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016861	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.954.158.030.500	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.696.663.850.014.040.500.500	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.519.389.310	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D016861	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15577	OCHV	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0085387	OCHV	LOOM
http://doe-generated-ontology.com/OntoAD#C0085387	ONTOAD	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024597	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.954.329.030.500	RH-MESH	LOOM
http://id.nlm.nih.gov/mesh/D016861	MDM	LOOM