Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Mercaptopurine
Synonyms	6 Mercaptopurine Monohydrate Purinethol
Definitions	An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
ID	http://purl.bioontology.org/ontology/MESH/D015122
altLabel	6 Mercaptopurine Monohydrate BW 57-323H BW 57323H 6H-Purine-6-thione, 1,7-dihydro- BW 57 323H Purimethol Puri-Nethol Mecaptopurine Anhydrous 6 Mercaptopurine 6-Mercaptopurine Mercaptopurina Wellcome 6 Thiohypoxanthine 6-Mercaptopurine Monohydrate 6-Thiohypoxanthine 1,7-Dihydro-6H-purine-6-thione Leupurin 6-Thiopurine 6 Thiopurine Purinethol
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0722911 C0000618 C0729098 C0729100 C0917847 C1563962 C0886849 C4279938
DC	1
definition	An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
DX	19850101
HN	2018(1985)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	PKK6MUZ20G E7WED276I5 0
isa	http://purl.bioontology.org/ontology/MESH/D000964 http://purl.bioontology.org/ontology/MESH/D000963 http://purl.bioontology.org/ontology/MESH/D007166 http://purl.bioontology.org/ontology/MESH/D019384
LT	TRD
Machine permutation	2018; see 6-Mecaptopurine 1985-2017; see MERCAPTOPURINE 1963-1984; see ARABINOSYL-6-MERCAPTOPURINE 1975-1991; MERCAPTOPURINE was indexed under 6-MERCAPTOPURINE 1975-1990
Mapped from	http://purl.bioontology.org/ontology/MESH/C045192 http://purl.bioontology.org/ontology/MESH/C077194 http://purl.bioontology.org/ontology/MESH/C497334 http://purl.bioontology.org/ontology/MESH/C097904 http://purl.bioontology.org/ontology/MESH/C488629 http://purl.bioontology.org/ontology/MESH/C059644 http://purl.bioontology.org/ontology/MESH/C578992 http://purl.bioontology.org/ontology/MESH/C045347 http://purl.bioontology.org/ontology/MESH/C100097 http://purl.bioontology.org/ontology/MESH/C020397 http://purl.bioontology.org/ontology/MESH/C104508 http://purl.bioontology.org/ontology/MESH/C521423 http://purl.bioontology.org/ontology/MESH/C010240 http://purl.bioontology.org/ontology/MESH/C011382 http://purl.bioontology.org/ontology/MESH/C042127 http://purl.bioontology.org/ontology/MESH/C572558 http://purl.bioontology.org/ontology/MESH/C045495 http://purl.bioontology.org/ontology/MESH/C080046 http://purl.bioontology.org/ontology/MESH/C061748 http://purl.bioontology.org/ontology/MESH/C083135 http://purl.bioontology.org/ontology/MESH/C067595 http://purl.bioontology.org/ontology/MESH/C107305 http://purl.bioontology.org/ontology/MESH/C018526 http://purl.bioontology.org/ontology/MESH/C046633 http://purl.bioontology.org/ontology/MESH/C413868 http://purl.bioontology.org/ontology/MESH/C098983 http://purl.bioontology.org/ontology/MESH/C078816 http://purl.bioontology.org/ontology/MESH/C057648 http://purl.bioontology.org/ontology/MESH/C079188 http://purl.bioontology.org/ontology/MESH/C037516 http://purl.bioontology.org/ontology/MESH/C046873 http://purl.bioontology.org/ontology/MESH/C017926 http://purl.bioontology.org/ontology/MESH/C121362 http://purl.bioontology.org/ontology/MESH/C050388 http://purl.bioontology.org/ontology/MESH/C092880 http://purl.bioontology.org/ontology/MESH/C497468 http://purl.bioontology.org/ontology/MESH/C471580 http://purl.bioontology.org/ontology/MESH/C471581 http://purl.bioontology.org/ontology/MESH/C471582 http://purl.bioontology.org/ontology/MESH/C098430 http://purl.bioontology.org/ontology/MESH/C518483 http://purl.bioontology.org/ontology/MESH/C064007 http://purl.bioontology.org/ontology/MESH/C099840 http://purl.bioontology.org/ontology/MESH/C438312 http://purl.bioontology.org/ontology/MESH/C076772 http://purl.bioontology.org/ontology/MESH/C084031 http://purl.bioontology.org/ontology/MESH/C037331 http://purl.bioontology.org/ontology/MESH/C530174 http://purl.bioontology.org/ontology/MESH/C010149 http://purl.bioontology.org/ontology/MESH/C078247 http://purl.bioontology.org/ontology/MESH/C004623 http://purl.bioontology.org/ontology/MESH/C108537 http://purl.bioontology.org/ontology/MESH/C064010 http://purl.bioontology.org/ontology/MESH/C046841 http://purl.bioontology.org/ontology/MESH/C047358 http://purl.bioontology.org/ontology/MESH/C047357 http://purl.bioontology.org/ontology/MESH/C000618571 http://purl.bioontology.org/ontology/MESH/C063925 http://purl.bioontology.org/ontology/MESH/C071948 http://purl.bioontology.org/ontology/MESH/C102061 http://purl.bioontology.org/ontology/MESH/C054950 http://purl.bioontology.org/ontology/MESH/C093739 http://purl.bioontology.org/ontology/MESH/C080913 http://purl.bioontology.org/ontology/MESH/C003149 http://purl.bioontology.org/ontology/MESH/C078216 http://purl.bioontology.org/ontology/MESH/C037167 http://purl.bioontology.org/ontology/MESH/C045311
MDA	19990101
MMR	20180705
MN	D03.633.100.759.570 D02.886.489.534
notation	D015122
PA	D019384 D000964 D007166 D000963
prefLabel	Mercaptopurine
RR	PKK6MUZ20G 6112-76-1 (monohydrate) 50-44-2 (6-Mercaptopurine)
TERMUI	T359701 T615997 T044182 T000942249 T044184 T044183 T044188 T044189 T044187 T000901871 T044186 T044190 T044185 T615998
TH	NLM (1997) US MX UK NL NLM (1999) NLM (1966) CA FDA SRS (2018) FDA SRS (2014) NLM (2019) ES UNK (19XX) INN (19XX) DE AU NLM (2017) USP (19XX) BAN (19XX) FR
tui	T114 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D011687 http://purl.bioontology.org/ontology/MESH/D013438

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/PDQ/CDR0000760529	PDQ	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/1039008	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D015122	MSHFRE	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/x02oo	RCD	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/CSP/2910-8664	CRISP	CUI
http://purl.bioontology.org/ontology/ATC/L01BB02	ATC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147079	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/002647	NDDF	CUI
http://purl.bioontology.org/ontology/SNMI/C-78160	SNMI	CUI
http://purl.bioontology.org/ontology/VANDF/4018776	VANDF	CUI
http://purl.bioontology.org/ontology/RCD/h33..	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D015122	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/386835005	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/LNC/MTHU002562	LOINC	CUI
http://purl.bioontology.org/ontology/SCTSPA/386835005	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/LNC/LP15173-5	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006010	NDFRT	CUI
http://purl.bioontology.org/ontology/RXNORM/103	RXNORM	CUI
http://purl.bioontology.org/ontology/SCTSPA/1039008	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006010	NDFRT	CUI
http://purl.obolibrary.org/obo/CHEBI_50667	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	OBA	LOOM
http://purl.bioontology.org/ontology/ATC/L01BB02	ATC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147079	NDFRT	LOOM
http://purl.obolibrary.org/obo/CHEBI_94796	FIDEO	LOOM
http://www.drugbank.ca/drugs/DB01033	FTC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassd6044246_0373_4b08_a498_d02a7370447e	WWECA	LOOM
http://purl.bioontology.org/ontology/NDDF/002647	NDDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C195	NCIT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78160	SNMI	LOOM
http://purl.bioontology.org/ontology/VANDF/4018776	VANDF	LOOM
http://purl.bioontology.org/ontology/RCD/h33..	RCD	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017416	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386835005	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002562	LOINC	LOOM
http://www.genomic-cds.org/ont/genomic-cds.owl#Mercaptopurine	GENE-CDS	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043436	PDQ	LOOM
http://www.co-ode.org/ontologies/galen#Mercaptopurine	GALEN	LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00918	COID	LOOM
https://go.drugbank.com/drugs/DB01033	MDM	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	CIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_50667	NIFSTD	LOOM
http://purl.bioontology.org/ontology/LNC/LP15173-5	LOINC	LOOM
http://purl.obolibrary.org/obo/NCIT_C195	BERO	LOOM
http://purl.bioontology.org/ontology/RXNORM/103	RXNORM	LOOM
http://doe-generated-ontology.com/OntoAD#C0000618	ONTOAD	LOOM