Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Tretinoin
Synonyms	beta all trans Retinoic Acid Retinoic Acid
Definitions	An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
ID	http://purl.bioontology.org/ontology/MESH/D014212
altLabel	beta all trans Retinoic Acid Retinoic acid Acid, beta-all-trans-Retinoic Tretinoin Potassium Salt Tretinoin Zinc Salt all-trans-Retinoic Acid Retin-A Vesanoid Salt, Tretinoin Potassium Sodium Salt, Tretinoin Salt, Tretinoin Zinc Acid, all-trans-Retinoic beta-all-trans-Retinoic Acid Zinc Salt, Tretinoin Vitamin A Acid Acid, trans-Retinoic Salt, Tretinoin Sodium Acid, Retinoic all trans Retinoic Acid trans Retinoic Acid trans-Retinoic Acid Retin A Acid, Vitamin A Potassium Salt, Tretinoin Tretinoin Sodium Salt Retinoic Acid
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui	C0886862 C0595126 C0593762 C0886864 C0886863 C0040845
DC	1
definition	An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
DX	19800101
FX	D018168
HN	80(75); was see under VITAMIN A 1975-79
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	75980-27-7 13497-05-7 5688UTC01R 0 22232-80-0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D018168
isa	http://purl.bioontology.org/ontology/MESH/D000970 http://purl.bioontology.org/ontology/MESH/D007641
LT	TRD
Machine permutation	80; was see under VITAMIN A 1975-79
Mapped from	http://purl.bioontology.org/ontology/MESH/C101473 http://purl.bioontology.org/ontology/MESH/C055167 http://purl.bioontology.org/ontology/MESH/C055168 http://purl.bioontology.org/ontology/MESH/C000723825 http://purl.bioontology.org/ontology/MESH/C053232 http://purl.bioontology.org/ontology/MESH/C519080 http://purl.bioontology.org/ontology/MESH/C546472 http://purl.bioontology.org/ontology/MESH/C059489 http://purl.bioontology.org/ontology/MESH/C496751 http://purl.bioontology.org/ontology/MESH/C033564 http://purl.bioontology.org/ontology/MESH/C033565 http://purl.bioontology.org/ontology/MESH/C044319 http://purl.bioontology.org/ontology/MESH/C475805 http://purl.bioontology.org/ontology/MESH/C009675 http://purl.bioontology.org/ontology/MESH/C041556 http://purl.bioontology.org/ontology/MESH/C045860 http://purl.bioontology.org/ontology/MESH/C066875 http://purl.bioontology.org/ontology/MESH/C089853 http://purl.bioontology.org/ontology/MESH/C520252 http://purl.bioontology.org/ontology/MESH/C036476 http://purl.bioontology.org/ontology/MESH/C044489 http://purl.bioontology.org/ontology/MESH/C006328 http://purl.bioontology.org/ontology/MESH/C117880 http://purl.bioontology.org/ontology/MESH/C050149 http://purl.bioontology.org/ontology/MESH/C111132 http://purl.bioontology.org/ontology/MESH/C505678 http://purl.bioontology.org/ontology/MESH/C505677 http://purl.bioontology.org/ontology/MESH/C557522 http://purl.bioontology.org/ontology/MESH/C557521 http://purl.bioontology.org/ontology/MESH/C078415 http://purl.bioontology.org/ontology/MESH/C077779 http://purl.bioontology.org/ontology/MESH/C091309 http://purl.bioontology.org/ontology/MESH/C067095 http://purl.bioontology.org/ontology/MESH/C010832 http://purl.bioontology.org/ontology/MESH/C100572 http://purl.bioontology.org/ontology/MESH/C100571 http://purl.bioontology.org/ontology/MESH/C518737 http://purl.bioontology.org/ontology/MESH/C080242 http://purl.bioontology.org/ontology/MESH/C558316 http://purl.bioontology.org/ontology/MESH/C046723 http://purl.bioontology.org/ontology/MESH/C026787 http://purl.bioontology.org/ontology/MESH/C061933 http://purl.bioontology.org/ontology/MESH/C073343 http://purl.bioontology.org/ontology/MESH/C034828 http://purl.bioontology.org/ontology/MESH/C018058 http://purl.bioontology.org/ontology/MESH/C002202 http://purl.bioontology.org/ontology/MESH/C061341 http://purl.bioontology.org/ontology/MESH/C061340 http://purl.bioontology.org/ontology/MESH/C054442 http://purl.bioontology.org/ontology/MESH/C054441 http://purl.bioontology.org/ontology/MESH/C064742 http://purl.bioontology.org/ontology/MESH/C503916 http://purl.bioontology.org/ontology/MESH/C077923 http://purl.bioontology.org/ontology/MESH/C524512 http://purl.bioontology.org/ontology/MESH/C000611302 http://purl.bioontology.org/ontology/MESH/C017597 http://purl.bioontology.org/ontology/MESH/C062265 http://purl.bioontology.org/ontology/MESH/C504501 http://purl.bioontology.org/ontology/MESH/C057861 http://purl.bioontology.org/ontology/MESH/C057860 http://purl.bioontology.org/ontology/MESH/C058346 http://purl.bioontology.org/ontology/MESH/C038961 http://purl.bioontology.org/ontology/MESH/C501864 http://purl.bioontology.org/ontology/MESH/C000606247 http://purl.bioontology.org/ontology/MESH/C508934 http://purl.bioontology.org/ontology/MESH/C412732 http://purl.bioontology.org/ontology/MESH/C575619 http://purl.bioontology.org/ontology/MESH/C112414 http://purl.bioontology.org/ontology/MESH/C105492 http://purl.bioontology.org/ontology/MESH/C107289 http://purl.bioontology.org/ontology/MESH/C107288 http://purl.bioontology.org/ontology/MESH/C559105 http://purl.bioontology.org/ontology/MESH/C022147 http://purl.bioontology.org/ontology/MESH/C560367 http://purl.bioontology.org/ontology/MESH/C031119 http://purl.bioontology.org/ontology/MESH/C035166 http://purl.bioontology.org/ontology/MESH/C464754 http://purl.bioontology.org/ontology/MESH/C034534 http://purl.bioontology.org/ontology/MESH/C019429 http://purl.bioontology.org/ontology/MESH/C026296 http://purl.bioontology.org/ontology/MESH/C038255 http://purl.bioontology.org/ontology/MESH/C581546 http://purl.bioontology.org/ontology/MESH/C039375 http://purl.bioontology.org/ontology/MESH/C058982
MDA	19741111
MMR	20200609
MN	D02.455.849.131.495.818.800 D02.455.326.271.665.202.495.818.500 D02.455.849.291.925.500 D02.455.426.392.368.367.379.249.700.860.500 D23.767.261.700.780
notation	D014212
PA	D000970 D007641
prefLabel	Tretinoin
RR	13497-05-7 (Na salt) 22232-80-0 (K salt) 302-79-4 (Tretinoin) 75980-27-7 (Zn salt)
TERMUI	T041632 T041636 T041633 T041629 T041630 T041634 T359744 T359742 T041635 T041631 T359743
TH	NLM (1997) NLM (1999) USAN (1970) FDA SRS (2014) UNK (19XX) INN (19XX) USP (19XX) BAN (19XX)
tui	T109 T131 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D014801 http://purl.bioontology.org/ontology/MESH/D012176

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D014212	MSHFRE	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041258	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/x03jL	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D014212	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D014212	MSHFRE	CUI
http://purl.bioontology.org/ontology/CSP/3147-4209	CRISP	CUI
http://purl.bioontology.org/ontology/RCD/x03ph	RCD	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041258	PDQ	CUI
http://purl.bioontology.org/ontology/RXNORM/153101	RXNORM	CUI
http://purl.bioontology.org/ontology/ATC/L01XF01	ATC	CUI
http://purl.bioontology.org/ontology/RCD/x03pf	RCD	CUI
http://purl.bioontology.org/ontology/SCTSPA/54972005	SCTSPA	CUI
http://purl.bioontology.org/ontology/MSHFRE/D014212	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDDF/001954	NDDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146871	NDFRT	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041258	PDQ	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/54972005	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005950	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387305002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/VANDF/4018550	VANDF	CUI
http://purl.bioontology.org/ontology/SNMI/C-92010	SNMI	CUI
http://purl.bioontology.org/ontology/ATC/D10AD01	ATC	CUI
http://purl.bioontology.org/ontology/RXNORM/10753	RXNORM	CUI
http://purl.bioontology.org/ontology/SCTSPA/387305002	SCTSPA	CUI
http://purl.bioontology.org/ontology/ATC/L01XF01	ATC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.767.261.700.780	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C900	BERO	LOOM
http://purl.bioontology.org/ontology/RCD/x03pf	RCD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.131.495.818.800	RH-MESH	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146871	NDFRT	LOOM
http://www.co-ode.org/ontologies/galen#Tretinoin	GALEN	LOOM
https://go.drugbank.com/drugs/DB00755	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.367.379.249.700.860.500	RH-MESH	LOOM
http://doe-generated-ontology.com/OntoAD#C0040845	ONTOAD	LOOM
http://www.drugbank.ca/drugs/DB00755	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12512	OCHV	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C900	NCIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.326.271.665.202.495.818.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041258	PDQ	LOOM
http://purl.obolibrary.org/obo/CHEBI_15367	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_15367	DRON	LOOM
http://purl.obolibrary.org/obo/MESH_D014212	BERO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387305002	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/OMIT_0015051	OMIT	LOOM
http://purl.bioontology.org/ontology/VANDF/4018550	VANDF	LOOM
http://purl.bioontology.org/ontology/SNMI/C-92010	SNMI	LOOM
http://purl.bioontology.org/ontology/ATC/D10AD01	ATC	LOOM
http://purl.obolibrary.org/obo/MCBCC_0000270#Tretinoin	MCBCC	LOOM
http://purl.jp/bio/4/id/200906081568041395	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040845	OCHV	LOOM
http://purl.bioontology.org/ontology/RXNORM/10753	RXNORM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016677	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014212	RH-MESH	LOOM