Medical Subject Headings

Last uploaded: April 29, 2019
Preferred Name

Sulindac

Synonyms

Chibret

Definitions

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

ID

http://purl.bioontology.org/ontology/MESH/D013467

altLabel

Chibret

Aclin

Nu-Sulindac

MK-231

Novo Sundac

Arthrocine

MK 231

Copal

Nu Sulindac

1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-

Arthrobid

Kenalin

MK231

Apo Sulin

Clinoril

Klinoril

Apo-Sulin

Novo-Sundac

Sulindal

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C1564277

C0733670

C1564273

C0733672

C1564275

C0591267

C1564274

C0038792

C1515040

C1515045

C1564276

DC

1

definition

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

DX

19900101

HN

90(79); was see under INDENES 1979-89

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

184SNS8VUH

0

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D004115

http://purl.bioontology.org/ontology/MESH/D007189

isa

http://purl.bioontology.org/ontology/MESH/D000970

http://purl.bioontology.org/ontology/MESH/D000894

http://purl.bioontology.org/ontology/MESH/D016861

LT

TRD

Machine permutation

90; was see under INDENES 1979-89

Mapped from

http://purl.bioontology.org/ontology/MESH/C431582

http://purl.bioontology.org/ontology/MESH/C452601

http://purl.bioontology.org/ontology/MESH/C553002

http://purl.bioontology.org/ontology/MESH/C543001

http://purl.bioontology.org/ontology/MESH/C539817

http://purl.bioontology.org/ontology/MESH/C571294

http://purl.bioontology.org/ontology/MESH/C526537

http://purl.bioontology.org/ontology/MESH/C025463

http://purl.bioontology.org/ontology/MESH/C439285

http://purl.bioontology.org/ontology/MESH/C508487

http://purl.bioontology.org/ontology/MESH/C025462

MDA

19780208

MMR

20160701

MN

D04.615.486.875

D02.455.426.559.847.486.875

notation

D013467

PA

D016861

D000894

D000970

prefLabel

Sulindac

RR

38194-50-2 (Sulindac)

TERMUI

T039517

T039515

T039516

T619221

T619219

T619223

T619215

T039514

T039519

T619213

T619217

T619211

T039518

T619224

TH

FDA SRS (2014)

USP (19XX)

US

NL

IE

UNK (19XX)

NLM (1990)

BAN (19XX)

CA

AU

MX

FR

INN (19XX)

UK

USAN (1975)

ES

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D007192

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013467 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/89505005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146307 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146307 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Sulindac GALEN LOOM
http://purl.bioontology.org/ontology/RCD/j2f.. RCD CUI
http://purl.bioontology.org/ontology/RCD/j2f.. RCD LOOM
http://scai.fraunhofer.de/AlzheimerOntology#sulindac ADO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://purl.bioontology.org/ontology/RCD/x02XZ RCD CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.486.875 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907040615001920 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4017957 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4017957 VANDF LOOM
http://data.bnf.fr/ark:/12148/cb12562840g FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/NDDF/002386 NDDF CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LP18100-5 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP18100-5 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.486.875 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 NIFSTD LOOM
http://d-nb.info/gnd/4358401-9 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000007042 NDFRT CUI
http://purl.bioontology.org/ontology/RXNORM/10237 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/10237 RXNORM LOOM
http://id.loc.gov/authorities/subjects/sh85130323 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387513000 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387513000 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906008974470052 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003386 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU003386 LOINC LOOM
http://www.drugbank.ca/drugs/DB00605 FTC LOOM
http://purl.bioontology.org/ontology/SNMI/C-60440 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-60440 SNMI LOOM
http://purl.bioontology.org/ontology/UATC/M01AB02 ATC CUI
http://purl.bioontology.org/ontology/UATC/M01AB02 ATC LOOM