Medical Subject Headings

Last uploaded: November 18, 2019
Preferred Name

Spironolactone

Synonyms

Spirogamma

Definitions

A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)

ID

http://purl.bioontology.org/ontology/MESH/D013148

altLabel

Spirogamma

Spirospare

Spiro L.U.T.

Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-

Duraspiron

Veroshpiron

Aquareduct

Verospiron

Spirono-Isis

Spiro Von Ct

Spiractin

Aldactone

SC9420

Aldactone A

Novo-Spiroton

NovoSpiroton

SC-9420

Flumach

Von Ct, Spiro

Espironolactona Mundogen

Spirono Isis

Espironolactona Alter

Verospirone

Practon

Spirolang

Frumikal

Novo Spiroton

Spirobeta

Spirolactone

Jenaspiron

Ct, Spiro Von

Spironone

SC 9420

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C1564162

C1564154

C1564193

C1564157

C0037982

C1564161

C1564194

C1564163

C0591054

C1564165

C1564173

C0592135

C0701468

C1564166

C0600340

C1564155

C1564156

C1564158

C1564174

C1564164

C0701471

C1564159

C1564160

DC

1

definition

A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)

DX

19660101

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

27O7W4T232

0

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D011420

http://purl.bioontology.org/ontology/MESH/D015107

http://purl.bioontology.org/ontology/MESH/D004116

http://purl.bioontology.org/ontology/MESH/D005003

http://purl.bioontology.org/ontology/MESH/D010852

http://purl.bioontology.org/ontology/MESH/D003683

http://purl.bioontology.org/ontology/MESH/D011282

http://purl.bioontology.org/ontology/MESH/D018942

http://purl.bioontology.org/ontology/MESH/D003348

http://purl.bioontology.org/ontology/MESH/D000077545

http://purl.bioontology.org/ontology/MESH/D014698

http://purl.bioontology.org/ontology/MESH/D011284

http://purl.bioontology.org/ontology/MESH/D061065

http://purl.bioontology.org/ontology/MESH/D000077403

http://purl.bioontology.org/ontology/MESH/D015025

http://purl.bioontology.org/ontology/MESH/D054742

isa

http://purl.bioontology.org/ontology/MESH/D000451

http://purl.bioontology.org/ontology/MESH/D004232

LT

TRD

Mapped from

http://purl.bioontology.org/ontology/MESH/C014143

http://purl.bioontology.org/ontology/MESH/C046565

http://purl.bioontology.org/ontology/MESH/C016699

http://purl.bioontology.org/ontology/MESH/C026063

http://purl.bioontology.org/ontology/MESH/C055913

http://purl.bioontology.org/ontology/MESH/C033554

http://purl.bioontology.org/ontology/MESH/C115981

http://purl.bioontology.org/ontology/MESH/C572034

http://purl.bioontology.org/ontology/MESH/C016210

http://purl.bioontology.org/ontology/MESH/C047175

http://purl.bioontology.org/ontology/MESH/C046564

http://purl.bioontology.org/ontology/MESH/C041006

http://purl.bioontology.org/ontology/MESH/C058243

http://purl.bioontology.org/ontology/MESH/C061691

http://purl.bioontology.org/ontology/MESH/C572033

http://purl.bioontology.org/ontology/MESH/C054537

http://purl.bioontology.org/ontology/MESH/C058412

http://purl.bioontology.org/ontology/MESH/C045343

http://purl.bioontology.org/ontology/MESH/C550428

http://purl.bioontology.org/ontology/MESH/C424563

http://purl.bioontology.org/ontology/MESH/C019225

http://purl.bioontology.org/ontology/MESH/C115980

http://purl.bioontology.org/ontology/MESH/C107482

http://purl.bioontology.org/ontology/MESH/C010768

http://purl.bioontology.org/ontology/MESH/C072356

http://purl.bioontology.org/ontology/MESH/C051308

http://purl.bioontology.org/ontology/MESH/C070473

http://purl.bioontology.org/ontology/MESH/C006286

http://purl.bioontology.org/ontology/MESH/C032299

http://purl.bioontology.org/ontology/MESH/C058465

http://purl.bioontology.org/ontology/MESH/C048998

http://purl.bioontology.org/ontology/MESH/C045746

MDA

19990101

MMR

20170524

MN

D02.540.679

D04.210.500.745.745.855

notation

D013148

PA

D004232

D000451

prefLabel

Spironolactone

RR

52-01-7 (Spironolactone)

TERMUI

T038655

T038659

T038653

T038657

T000912891

T618534

T618544

T618590

T618548

T038652

T618524

T618594

T618733

T618538

T618592

T038654

T618542

T618540

T038656

T000912890

T618532

T618528

T038658

T618731

T618530

T618536

TH

FDA SRS (2014)

USP (19XX)

US

UNK (19XX)

DE

NLM (1990)

BAN (19XX)

NLM (1996)

CA

AU

FR

INN (19XX)

UK

ES

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D011283

http://purl.bioontology.org/ontology/MESH/D007783

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http://purl.bioontology.org/ontology/MSHFRE/D013148 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D013148 MSHFRE CUI
http://purl.bioontology.org/ontology/RCD/b43.. RCD CUI
http://purl.bioontology.org/ontology/RCD/b43.. RCD LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C840 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C840 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-72420 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-72420 SNMI LOOM
http://purl.bioontology.org/ontology/SCTSPA/13929005 SCTSPA CUI
http://purl.bioontology.org/ontology/SNMI/C-C10CE SNMI CUI
http://purl.bioontology.org/ontology/NDDF/002211 NDDF CUI
http://purl.bioontology.org/ontology/RCD/x02rR RCD CUI
http://purl.jp/bio/4/id/200906028579154843 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP16280-7 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP16280-7 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/x02T5 RCD CUI
http://purl.bioontology.org/ontology/CSP/2794-2536 CRISP CUI
http://purl.bioontology.org/ontology/CSP/2794-2536 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.745.745.855 RH-MESH LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#spironolactone FASTO LOOM
http://www.ifomis.org/acgt/1.0#Spironolactone ACGT-MO LOOM
http://purl.bioontology.org/ontology/UATC/C03DA01 ATC CUI
http://purl.bioontology.org/ontology/UATC/C03DA01 ATC LOOM
http://purl.bioontology.org/ontology/SCTSPA/387078006 SCTSPA CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.540.679 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003227 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU003227 LOINC LOOM
http://www.drugbank.ca/drugs/DB00421 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4017881 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4017881 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146234 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146234 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013148 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9241 NIFSTD LOOM
http://purl.obolibrary.org/obo/XCO_0000627 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000627 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000627 XCO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/13929005 SNOMEDCT CUI
http://www.co-ode.org/ontologies/galen#Spironolactone GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/9997 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/9997 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000005900 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387078006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387078006 SNOMEDCT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0037982 HFO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039444 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039444 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039444 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039444 PDQ LOOM
http://stirdf.jst.go.jp/id/200907023665510166 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/151317 RXNORM CUI
http://sbmi.uth.tmc.edu/ontology/ochv#C0037982 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11637 OCHV LOOM