An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
ID
http://purl.bioontology.org/ontology/MESH/D011802
altLabel
Sulfate, Quinidine
Quinidine Sulfate
Adaquin
Chinidin
Quinora
Cinchonan-9-ol, 6'-methoxy-, (9S)-
Apo-Quinidine
Apo Quinidine
Quinidex
Quincardine
AQL
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui
C0034436
C0034414
C1564019
C1564020
C1564018
C0034415
C1564021
DC
1
definition
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.