Medical Subject Headings

Last uploaded: August 27, 2019
Preferred Name

Tissue Plasminogen Activator

Synonyms

Alteplase

Definitions

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

ID

http://purl.bioontology.org/ontology/MESH/D010959

altLabel

Alteplase

Actilyse

Plasminogen Activator, Tissue-Type

Lysatec rtPA

TTPA

Activase

Plasminogen Activator, Tissue

Plasminogen Activator, Tissue Type

Lysatec rt PA

Tissue-Type Plasminogen Activator

T Plasminogen Activator

Tissue Activator D 44

Tissue Activator D-44

Tisokinase

Lysatec rt-PA

T-Plasminogen Activator

Tissue Type Plasminogen Activator

AQL

AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR

cui

C0032143

C0701942

C0678113

DC

1

definition

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

DX

19860101

HN

98(86)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

EC 3.4.21.68

0

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D017244

http://purl.bioontology.org/ontology/MESH/D013381

http://purl.bioontology.org/ontology/MESH/D045702

http://purl.bioontology.org/ontology/MESH/D015956

http://purl.bioontology.org/ontology/MESH/D010960

http://purl.bioontology.org/ontology/MESH/D010196

http://purl.bioontology.org/ontology/MESH/D013300

http://purl.bioontology.org/ontology/MESH/D045706

http://purl.bioontology.org/ontology/MESH/D004765

http://purl.bioontology.org/ontology/MESH/D011415

http://purl.bioontology.org/ontology/MESH/D011402

http://purl.bioontology.org/ontology/MESH/D053804

http://purl.bioontology.org/ontology/MESH/D005341

http://purl.bioontology.org/ontology/MESH/D010977

http://purl.bioontology.org/ontology/MESH/D005344

http://purl.bioontology.org/ontology/MESH/D015945

http://purl.bioontology.org/ontology/MESH/D050606

http://purl.bioontology.org/ontology/MESH/D005170

http://purl.bioontology.org/ontology/MESH/D013925

http://purl.bioontology.org/ontology/MESH/D000074923

http://purl.bioontology.org/ontology/MESH/D011416

http://purl.bioontology.org/ontology/MESH/D000074289

http://purl.bioontology.org/ontology/MESH/D007610

http://purl.bioontology.org/ontology/MESH/D000071449

http://purl.bioontology.org/ontology/MESH/D053818

http://purl.bioontology.org/ontology/MESH/D002118

http://purl.bioontology.org/ontology/MESH/D005340

http://purl.bioontology.org/ontology/MESH/D019286

http://purl.bioontology.org/ontology/MESH/D010972

http://purl.bioontology.org/ontology/MESH/D007781

http://purl.bioontology.org/ontology/MESH/D013917

http://purl.bioontology.org/ontology/MESH/D005172

http://purl.bioontology.org/ontology/MESH/D053146

http://purl.bioontology.org/ontology/MESH/D005165

http://purl.bioontology.org/ontology/MESH/D020791

http://purl.bioontology.org/ontology/MESH/D015951

http://purl.bioontology.org/ontology/MESH/D014357

http://purl.bioontology.org/ontology/MESH/D000176

http://purl.bioontology.org/ontology/MESH/D015942

http://purl.bioontology.org/ontology/MESH/D011516

http://purl.bioontology.org/ontology/MESH/D005176

http://purl.bioontology.org/ontology/MESH/D056649

http://purl.bioontology.org/ontology/MESH/D005169

http://purl.bioontology.org/ontology/MESH/D007704

http://purl.bioontology.org/ontology/MESH/D045664

http://purl.bioontology.org/ontology/MESH/D001620

http://purl.bioontology.org/ontology/MESH/D014568

http://purl.bioontology.org/ontology/MESH/D015849

http://purl.bioontology.org/ontology/MESH/D002918

http://purl.bioontology.org/ontology/MESH/D005167

http://purl.bioontology.org/ontology/MESH/D045683

http://purl.bioontology.org/ontology/MESH/D010978

http://purl.bioontology.org/ontology/MESH/D005345

http://purl.bioontology.org/ontology/MESH/D005164

http://purl.bioontology.org/ontology/MESH/D014841

http://purl.bioontology.org/ontology/MESH/D053802

http://purl.bioontology.org/ontology/MESH/D005174

http://purl.bioontology.org/ontology/MESH/D015949

isa

http://purl.bioontology.org/ontology/MESH/D005343

LT

TRD

Machine permutation

98; see ALTEPLASE 1992-97; see PLASMINOGEN ACTIVATOR, TISSUE-TYPE 1986-91

Mapped from

http://purl.bioontology.org/ontology/MESH/C083866

http://purl.bioontology.org/ontology/MESH/C081981

http://purl.bioontology.org/ontology/MESH/C065736

http://purl.bioontology.org/ontology/MESH/C087896

http://purl.bioontology.org/ontology/MESH/C067262

http://purl.bioontology.org/ontology/MESH/C077412

http://purl.bioontology.org/ontology/MESH/C080391

http://purl.bioontology.org/ontology/MESH/C083865

http://purl.bioontology.org/ontology/MESH/C085027

http://purl.bioontology.org/ontology/MESH/C449559

http://purl.bioontology.org/ontology/MESH/C089949

http://purl.bioontology.org/ontology/MESH/C068645

http://purl.bioontology.org/ontology/MESH/C473928

http://purl.bioontology.org/ontology/MESH/C059835

http://purl.bioontology.org/ontology/MESH/C072781

http://purl.bioontology.org/ontology/MESH/C550736

http://purl.bioontology.org/ontology/MESH/C567341

http://purl.bioontology.org/ontology/MESH/C065621

http://purl.bioontology.org/ontology/MESH/C104096

MDA

19850612

MMR

20160701

MN

D08.811.277.656.300.760.875

D12.776.124.125.662.768

D08.811.277.656.959.350.875

D23.119.970

notation

D010959

PA

D005343

prefLabel

Tissue Plasminogen Activator

RR

105857-23-6 (Alteplase)

TERMUI

T032267

T032270

T032273

T707756

T032272

T032269

T365869

T032268

T032266

T505964

T032271

TH

NLM (1998)

US

NL

IE

UNK (19XX)

NLM (1992)

DE

JAN (19XX)

NLM (2009)

BAN (19XX)

CA

NLM (2000)

AU

MX

USAN (1989)

NLM (1999)

INN (19XX)

UK

ES

tui

T116

T121

T126

subClassOf

http://purl.bioontology.org/ontology/MESH/D010960

http://purl.bioontology.org/ontology/MESH/D001779

http://purl.bioontology.org/ontology/MESH/D012697

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/NDFRT/N0000147695 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4019319 VANDF CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387152000 SNOMEDCT CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010959 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-A7410 SNMI CUI
http://purl.bioontology.org/ontology/RXNORM/8410 RXNORM CUI
http://purl.bioontology.org/ontology/SNOMEDCT/27638005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNMI/F-D7A20 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/F-D7A20 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.277.656.959.350.875 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.124.125.662.768 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/108997009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/387152000 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/002074 NDDF CUI
http://purl.bioontology.org/ontology/CSP/0437-7160 CRISP CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007047 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4019599 VANDF CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.119.970 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP16891-1 LOINC CUI
http://purl.bioontology.org/ontology/RCD/bv3.. RCD CUI
http://purl.bioontology.org/ontology/RCD/x02Sk RCD CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042033 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042033 PDQ CUI
http://purl.bioontology.org/ontology/SNOMEDCT/37411004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/37411004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SCTSPA/37411004 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/S01XA13 ATC CUI
http://purl.bioontology.org/ontology/SCTSPA/27638005 SCTSPA CUI
http://purl.bioontology.org/ontology/SNMI/C-C1080 SNMI CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.277.656.300.760.875 RH-MESH LOOM
http://purl.bioontology.org/ontology/MSHFRE/D010959 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D010959 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D010959 MSHFRE CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147508 NDFRT CUI
http://purl.bioontology.org/ontology/UATC/B01AD02 ATC CUI
http://ccdb.ucsd.edu/SAO/1.2#sao681020632 SAO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU019721 LOINC CUI
http://id.loc.gov/authorities/subjects/sh87000090 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SCTSPA/108997009 SCTSPA CUI
http://purl.bioontology.org/ontology/RXNORM/204210 RXNORM CUI
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_e7712dbb_ef45_4044_990c_203b584b3d10 CVAO LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_e7712dbb_ef45_4044_990c_203b584b3d10 STO-DRAFT LOOM
http://uri.neuinfo.org/nif/nifstd/sao681020632 NIFSTD LOOM