loading...| Preferred Name |
Oncogenes |
|
| Synonyms |
Transforming Gene Oncogene |
|
| Definitions |
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D009857 |
|
| altLabel |
Transforming Gene Gene, Transforming Transforming Genes Genes, Transforming Oncogene |
|
| AN |
"oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM |
|
| AQL |
DE ES GE IM PH RE |
|
| cui |
C0029016 |
|
| DC |
1 |
|
| definition |
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene. |
|
| DX |
19830101 |
|
| HN |
83 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Machine permutation |
83 |
|
| Mapped from | ||
| MDA |
19820422 |
|
| MMR |
20080708 |
|
| MN |
G05.360.340.024.340.375.500 |
|
| notation |
D009857 |
|
| prefLabel |
Oncogenes |
|
| TERMUI |
T029231 T029234 T029233 T029232 |
|
| TH |
NLM (1991) UNK (19XX) NLM (1988) NLM (1983) |
|
| tui |
T028 |
|
| subClassOf |