Medical Subject Headings

Last uploaded: August 27, 2019
Preferred Name

Nitric Oxide

Synonyms

Nitric Oxide, Endothelium Derived

Definitions

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

ID

http://purl.bioontology.org/ontology/MESH/D009569

altLabel

Nitric Oxide, Endothelium Derived

Endothelium-Derived Nitric Oxide

Nitrate Vasodilator, Endogenous

Nitrogen Monoxide

Endogenous Nitrate Vasodilator

Nitrogen oxide (NO)

Mononitrogen Monoxide

Monoxide, Mononitrogen

Oxide, Nitric

Nitric Oxide, Endothelium-Derived

Vasodilator, Endogenous Nitrate

Monoxide, Nitrogen

AQL

AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR

cui

C0028128

DC

1

definition

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

DX

19650101

FX

D020030

D045462

HN

1965

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

31C4KY9ESH

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D045462

http://purl.bioontology.org/ontology/MESH/D020030

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D009585

http://purl.bioontology.org/ontology/MESH/D017382

http://purl.bioontology.org/ontology/MESH/D009609

http://purl.bioontology.org/ontology/MESH/D030421

isa

http://purl.bioontology.org/ontology/MESH/D016166

http://purl.bioontology.org/ontology/MESH/D045462

http://purl.bioontology.org/ontology/MESH/D064426

http://purl.bioontology.org/ontology/MESH/D018377

http://purl.bioontology.org/ontology/MESH/D001993

Machine permutation

1965

Mapped from

http://purl.bioontology.org/ontology/MESH/C498979

http://purl.bioontology.org/ontology/MESH/C110153

http://purl.bioontology.org/ontology/MESH/C000594696

http://purl.bioontology.org/ontology/MESH/C106536

http://purl.bioontology.org/ontology/MESH/C504137

http://purl.bioontology.org/ontology/MESH/C110152

http://purl.bioontology.org/ontology/MESH/C088437

http://purl.bioontology.org/ontology/MESH/C112653

http://purl.bioontology.org/ontology/MESH/C058377

http://purl.bioontology.org/ontology/MESH/C000596989

http://purl.bioontology.org/ontology/MESH/C093551

http://purl.bioontology.org/ontology/MESH/C544422

MDA

19990101

MMR

20130708

MN

D01.650.550.587.600

D01.625.550.500

D01.625.700.500

D01.339.387

notation

D009569

PA

D045462

D018377

D064426

D016166

D001993

prefLabel

Nitric Oxide

RR

10102-43-9 (Nitric Oxide)

TERMUI

T046281

T046285

T028507

T028510

T028508

TH

FDA SRS (2014)

NLM (1965)

UNK (19XX)

USAN (19XX)

NLM (1990)

NLM (1994)

NLM (1999)

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D009589

http://purl.bioontology.org/ontology/MESH/D026361

http://purl.bioontology.org/ontology/MESH/D005609

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