Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Metolazone
Synonyms	Zaroxolyn
Definitions	A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
ID	http://purl.bioontology.org/ontology/MESH/D008788
altLabel	Zaroxolyn Microx Mykrox SR72022 SR 720 22 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo- SR-720-22 Diulo
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0701385 C0701386 C0025854 C0701383 C0701384
DC	1
definition	A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
DX	19910101
HN	91(75); was see under DIURETICS, SULFAMYL 1975-90
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	TZ7V40X7VX 0
isa	http://purl.bioontology.org/ontology/MESH/D000959 http://purl.bioontology.org/ontology/MESH/D004232 http://purl.bioontology.org/ontology/MESH/D049993
LT	TRD
Machine permutation	91; was see under DIURETICS, SULFAMYL 1975-90
MDA	19741111
MMR	20170524
MN	D02.065.884.600 D02.886.590.700.600 D03.633.100.786.830.688
notation	D008788
PA	D000959 D049993 D004232
prefLabel	Metolazone
RR	17560-51-9 (Metolazone)
TERMUI	T026225 T026222 T814664 T026224 T026223 T026221
TH	US USAN (1968) FDA SRS (2014) UNK (19XX) INN (19XX) NLM (2013) USP (19XX) BAN (19XX)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D052999 http://purl.bioontology.org/ontology/MESH/D013449

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SNMI/C-C173A	SNMI	CUI
http://purl.bioontology.org/ontology/LNC/LP17954-6	LOINC	CUI
http://purl.bioontology.org/ontology/MSHFRE/D008788	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D008788	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-72290	SNMI	CUI
http://purl.bioontology.org/ontology/SCTSPA/22198003	SCTSPA	CUI
http://purl.bioontology.org/ontology/SCTSPA/387123003	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/MTHU060443	LOINC	CUI
http://purl.bioontology.org/ontology/VANDF/4018161	VANDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005746	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/22198003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/RXNORM/6916	RXNORM	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146498	NDFRT	CUI
http://purl.bioontology.org/ontology/ATC/C03BA08	ATC	CUI
http://purl.bioontology.org/ontology/RCD/b2b..	RCD	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387123003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/CSP/0394-7343	CRISP	CUI
http://purl.bioontology.org/ontology/NDDF/002310	NDDF	CUI
http://purl.obolibrary.org/obo/CHEBI_64354	CHEBI	LOOM
http://purl.bioontology.org/ontology/LNC/LP17954-6	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008788	RH-MESH	LOOM
http://www.co-ode.org/ontologies/galen#Metolazone	GALEN	LOOM
http://purl.obolibrary.org/obo/OMIT_0009844	OMIT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-72290	SNMI	LOOM
http://purl.obolibrary.org/obo/NCIT_C650	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_64354	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_64354	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_64354	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_64354	DRON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025854	OCHV	LOOM
http://purl.jp/bio/4/id/200906012553796770	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D008788	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8070	OCHV	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015958	PMAPP-PMO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146498	ODAE	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146498	KTAO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.700.600	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060443	LOINC	LOOM
http://purl.bioontology.org/ontology/VANDF/4018161	VANDF	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0025854	HFO	LOOM
http://www.drugbank.ca/drugs/DB00524	FTC	LOOM
http://stirdf.jst.go.jp/id/200907052666475291	IOBC	LOOM
http://purl.bioontology.org/ontology/RXNORM/6916	RXNORM	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146498	NDFRT	LOOM
http://purl.bioontology.org/ontology/ATC/C03BA08	ATC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.786.830.688	RH-MESH	LOOM
http://purl.obolibrary.org/obo/DRON_00015990	ODNAE	LOOM
http://purl.bioontology.org/ontology/RCD/b2b..	RCD	LOOM
https://go.drugbank.com/drugs/DB00524	MDM	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C650	NCIT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387123003	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/NDDF/002310	NDDF	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.884.600	RH-MESH	LOOM