The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
ID
http://purl.bioontology.org/ontology/MESH/D007980
altLabel
L-Dopa
L 3,4 Dihydroxyphenylalanine
3 Hydroxy L tyrosine
L-3,4-Dihydroxyphenylalanine
3-Hydroxy-L-tyrosine
Dopaflex
Dopar
Levopa
L Dopa
Larodopa
AQL
AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui
C1449995
C0023570
C0700880
C0699991
C0720022
DC
1
definition
The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
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