loading...| Preferred Name |
Dextromethorphan |
|
| Synonyms |
Dextromethorphan Hydrobromide, Monohydrate |
|
| Definitions |
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D003915 |
|
| altLabel |
Dextromethorphan Hydrobromide, Monohydrate d-Methorphan Dextromethorphan Hydrobromide, (+-)-Isomer Hydrobromide, Dextromethorphan Dextromethorphan Hydrobromide Racemethorphan Dextromethorphan Hydrochloride Dextromethorphan, (+-)-Isomer Hydrochloride, Dextromethorphan Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)- Delsym |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0011816 C0887411 C0887413 C0350422 C0034505 C0916919 C0011218 C0887412 |
|
| DC |
1 |
|
| definition |
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity. |
|
| DX |
19910101 |
|
| HN |
91(72); was see under LEVORPHANOL 1972-90 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
6700-34-1 6031-86-3 7355X3ROTS 9D2RTI9KYH 351KFH969D 8YB8F78WM1 0 510-53-2 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
91; was see under LEVORPHANOL 1972-90 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C045626 http://purl.bioontology.org/ontology/MESH/C023705 http://purl.bioontology.org/ontology/MESH/C548636 http://purl.bioontology.org/ontology/MESH/C426724 http://purl.bioontology.org/ontology/MESH/C054116 http://purl.bioontology.org/ontology/MESH/C042497 http://purl.bioontology.org/ontology/MESH/C121608 http://purl.bioontology.org/ontology/MESH/C049111 http://purl.bioontology.org/ontology/MESH/C479098 http://purl.bioontology.org/ontology/MESH/C507057 http://purl.bioontology.org/ontology/MESH/C550887 |
|
| MDA |
19990101 |
|
| MMR |
20230531 |
|
| MN |
D03.633.400.686.212 D03.132.577.249.200 D03.605.497.212 D04.615.723.795.200 |
|
| notation |
D003915 |
|
| PA |
D018691 D000996 |
|
| prefLabel |
Dextromethorphan |
|
| RR |
125-71-3 (Dextromethorphan) 6031-86-3 (HBr, (+-)-isomer) 18609-21-7 (HCl) 125-68-8 (HBr, cpd w/o isomeric designation) 9D2RTI9KYH 510-53-2 ((+-)-isomer) 351KFH969D 125-69-9 (HBr) 8YB8F78WM1 6700-34-1 (HBr, mono-hydrate) |
|
| TERMUI |
T360714 T011712 T011715 T360713 T360712 T360716 T011713 T360715 T011711 |
|
| TH |
NLM (1999) FDA SRS (2014) UNK (19XX) INN (19XX) USP (19XX) BAN (19XX) |
|
| tui |
T109 T121 |
|
| subClassOf |