A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
ID
http://purl.bioontology.org/ontology/MESH/D003622
altLabel
Avlosulfone
DADPS
Sulfonyldianiline
4,4' Diaminophenyl Sulfone
Sulfone, 4,4'-Diaminophenyl
Diaminodiphenylsulfone
Dapsoderm-X
Dapson-Fatol
4,4'-Diaminophenyl Sulfone
Sulfona
Diaphenylsulfone
Disulone
AQL
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui
C1569265
C0729116
C0010980
C1569263
C0729115
C1569264
DC
1
definition
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)