An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
ID
http://purl.bioontology.org/ontology/MESH/D003022
altLabel
FB b 5097
Canesten
Lotrimin
Bay b 5097
Klotrimazole
Mycelex
1H-Imidazole, 1-((2-chlorophenyl)diphenylmethyl)-
Kanesten
AQL
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui
C0699670
C0701173
C0009074
C0699669
C0701174
C0699671
DC
1
definition
An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
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