Medical Subject Headings

Last uploaded: August 27, 2019
Preferred Name

Amiloride

Synonyms

Anhydrous Amiloride Hydrochloride

Definitions

A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)

ID

http://purl.bioontology.org/ontology/MESH/D000584

altLabel

Anhydrous Amiloride Hydrochloride

Amiloberag

Amiloride Hydrochloride, Anhydrous

Hydrochloride, Amiloride

Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-

Amiduret Trom

Amiloride Hydrochloride

Kaluril

Modamide

Midoride

Midamor

Amidal

Trom, Amiduret

Hydrochloride, Anhydrous Amiloride

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C0718462

C1448394

C0949217

C1448396

C0026054

C0002502

C1448395

C1448397

C0546849

DC

1

definition

A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)

DX

19860101

HN

86(72); was see under PYRAZINES 1975-85, was Prov 1972-74

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

FZJ37245UC

0

2016-88-8

7DZO8EB0Z3

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D011718

http://purl.bioontology.org/ontology/MESH/D000068900

http://purl.bioontology.org/ontology/MESH/D000069286

http://purl.bioontology.org/ontology/MESH/D000069582

isa

http://purl.bioontology.org/ontology/MESH/D004232

http://purl.bioontology.org/ontology/MESH/D062686

http://purl.bioontology.org/ontology/MESH/D062646

LT

TRD

Machine permutation

86; was see under PYRAZINES 1975-85

Mapped from

http://purl.bioontology.org/ontology/MESH/C064150

http://purl.bioontology.org/ontology/MESH/C000604937

http://purl.bioontology.org/ontology/MESH/C046878

http://purl.bioontology.org/ontology/MESH/C049046

http://purl.bioontology.org/ontology/MESH/C047088

http://purl.bioontology.org/ontology/MESH/C013407

http://purl.bioontology.org/ontology/MESH/C053494

http://purl.bioontology.org/ontology/MESH/C076305

http://purl.bioontology.org/ontology/MESH/C000592315

http://purl.bioontology.org/ontology/MESH/C055284

http://purl.bioontology.org/ontology/MESH/C058269

http://purl.bioontology.org/ontology/MESH/C047657

http://purl.bioontology.org/ontology/MESH/C040679

http://purl.bioontology.org/ontology/MESH/C056107

http://purl.bioontology.org/ontology/MESH/C066056

http://purl.bioontology.org/ontology/MESH/C051584

http://purl.bioontology.org/ontology/MESH/C054391

http://purl.bioontology.org/ontology/MESH/C064515

http://purl.bioontology.org/ontology/MESH/C050820

http://purl.bioontology.org/ontology/MESH/C063513

http://purl.bioontology.org/ontology/MESH/C061007

http://purl.bioontology.org/ontology/MESH/C044677

http://purl.bioontology.org/ontology/MESH/C084633

http://purl.bioontology.org/ontology/MESH/C584412

http://purl.bioontology.org/ontology/MESH/C070708

http://purl.bioontology.org/ontology/MESH/C056369

http://purl.bioontology.org/ontology/MESH/C029230

http://purl.bioontology.org/ontology/MESH/C048793

http://purl.bioontology.org/ontology/MESH/C039614

http://purl.bioontology.org/ontology/MESH/C066916

http://purl.bioontology.org/ontology/MESH/C051690

http://purl.bioontology.org/ontology/MESH/C058206

http://purl.bioontology.org/ontology/MESH/C081564

http://purl.bioontology.org/ontology/MESH/C039465

http://purl.bioontology.org/ontology/MESH/C010247

http://purl.bioontology.org/ontology/MESH/C050819

http://purl.bioontology.org/ontology/MESH/C043988

http://purl.bioontology.org/ontology/MESH/C063512

http://purl.bioontology.org/ontology/MESH/C057360

http://purl.bioontology.org/ontology/MESH/C076306

http://purl.bioontology.org/ontology/MESH/C053837

http://purl.bioontology.org/ontology/MESH/C041470

http://purl.bioontology.org/ontology/MESH/C076676

http://purl.bioontology.org/ontology/MESH/C067984

http://purl.bioontology.org/ontology/MESH/C421266

http://purl.bioontology.org/ontology/MESH/C034428

http://purl.bioontology.org/ontology/MESH/C046793

http://purl.bioontology.org/ontology/MESH/C029229

MDA

19990101

MMR

20170524

MN

D03.383.679.149

notation

D000584

PA

D004232

D062686

D062646

prefLabel

Amiloride

RR

FZJ37245UC

2609-46-3 (Amiloride)

2016-88-8

17440-83-4 (Amiloride Hydrochloride)

TERMUI

T506671

T506665

T001777

T360951

T506667

T001775

T506669

T001776

T506664

T506673

TH

FDA SRS (2014)

USP (19XX)

US

NL

IE

DE

USAN (1967)

BAN (19XX)

CA

AU

FR

NLM (1999)

INN (19XX)

UK

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D011719

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http://purl.bioontology.org/ontology/MSHFRE/D000584 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D000584 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D000584 MSHFRE CUI
http://purl.bioontology.org/ontology/RXNORM/6958 RXNORM CUI
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http://purl.bioontology.org/ontology/NDFRT/N0000147699 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP16024-9 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP16024-9 LOINC LOOM
http://www.drugbank.ca/drugs/DB00594 FTC LOOM
http://purl.bioontology.org/ontology/UATC/C03DB01 ATC CUI
http://purl.bioontology.org/ontology/UATC/C03DB01 ATC LOOM
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http://purl.bioontology.org/ontology/NDFRT/N0000146285 NDFRT CUI
http://purl.bioontology.org/ontology/RCD/x02j1 RCD CUI
https://bioportal.bioontology.org/ontologies/FTDM.owl#amiloride FASTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387516008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/LNC/MTHU006775 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU006775 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002502 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/C-72410 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-72410 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/87395005 SNOMEDCT CUI
http://www.co-ode.org/ontologies/galen#Amiloride GALEN LOOM
http://purl.jp/bio/4/id/200906066759071490 IOBC LOOM
http://purl.bioontology.org/ontology/SCTSPA/387503008 SCTSPA CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000584 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2639 FYPO LOOM
http://id.loc.gov/authorities/subjects/sh85004476 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RXNORM/644 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/644 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/002316 NDDF CUI
http://purl.bioontology.org/ontology/RCD/x01Qu RCD CUI
http://purl.bioontology.org/ontology/RCD/x01Qu RCD LOOM
http://stirdf.jst.go.jp/id/200907033781089260 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000006772 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/87395005 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/004861 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/004861 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61633 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61633 NCIT LOOM
http://purl.bioontology.org/ontology/SCTSPA/387516008 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387503008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387503008 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.679.149 RH-MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0002502 HFO LOOM
http://purl.bioontology.org/ontology/RXNORM/142424 RXNORM CUI