loading...| Preferred Name |
Certolizumab Pegol |
|
| Synonyms |
Cimzia |
|
| Definitions |
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000068582 |
|
| altLabel |
Cimzia CDP 870 CDP870 |
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PK PO RE TO TU UL UR |
|
| cui |
C1172157 C1872109 C2343521 |
|
| DC |
1 |
|
| definition |
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. |
|
| DX |
20160101 |
|
| FX |
D014409 |
|
| HN |
2016 (2003) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 |
|
| Inverse of RB |
UMD07X179E 0 |
|
| Inverse of RO | ||
| isa |
http://purl.bioontology.org/ontology/MESH/D000079424 |
|
| LT |
TRD |
|
| Machine permutation |
2016; CERTILIZUMAB PEGOL was indexed under IMMUNOGLOBULIN FAB FRAGMENTS 2003-2015, POLYETHYLENE GLYCOLS 2003-2015, and under ANTIBODIES, MONOCLONAL, HUMANIZED 2003-2015 |
|
| MDA |
20150710 |
|
| MMR |
20210701 |
|
| MN |
D12.644.541.500.650.250 D12.776.377.715.548.680.650.250 D12.776.124.790.651.680.650.250 D05.750.741.125 D12.776.124.486.485.680.650.250 D12.776.377.715.548.114.224.200.500 D12.776.124.486.485.114.224.060.500 D12.776.124.790.651.114.224.060.500 |
|
| notation |
D000068582 |
|
| PA |
D018501 D000079424 D007166 |
|
| prefLabel |
Certolizumab Pegol |
|
| RR |
428863-50-7 |
|
| TERMUI |
T526396 T526395 T794930 T000876351 |
|
| TH |
NLM (2002) FDA SRS (2013) NLM (2012) USAN (19XX) NLM (2007) |
|
| tui |
T116 T129 T121 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D007140 |