Medical Subject Headings

Last uploaded: April 29, 2019
Preferred Name

Aripiprazole

Synonyms

OPC 14597

Definitions

A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.

ID

http://purl.bioontology.org/ontology/MESH/D000068180

altLabel

OPC 14597

7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone

OPC-14597

Abilify

Aripiprazol

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C1170019

C0950934

C0299792

DC

1

definition

A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.

DX

20160101

HN

2016 (1995)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

Inverse of RB

0

82VFR53I78

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D014196

http://purl.bioontology.org/ontology/MESH/D000068799

http://purl.bioontology.org/ontology/MESH/D000078784

http://purl.bioontology.org/ontology/MESH/D010885

http://purl.bioontology.org/ontology/MESH/D005444

http://purl.bioontology.org/ontology/MESH/D011447

http://purl.bioontology.org/ontology/MESH/D000068677

http://purl.bioontology.org/ontology/MESH/D007654

http://purl.bioontology.org/ontology/MESH/D000077489

http://purl.bioontology.org/ontology/MESH/D042462

http://purl.bioontology.org/ontology/MESH/D002065

http://purl.bioontology.org/ontology/MESH/D019307

http://purl.bioontology.org/ontology/MESH/D013847

http://purl.bioontology.org/ontology/MESH/D000069058

http://purl.bioontology.org/ontology/MESH/D045542

http://purl.bioontology.org/ontology/MESH/D017964

http://purl.bioontology.org/ontology/MESH/D004246

http://purl.bioontology.org/ontology/MESH/D003501

http://purl.bioontology.org/ontology/MESH/D000068877

http://purl.bioontology.org/ontology/MESH/D008013

http://purl.bioontology.org/ontology/MESH/D006531

http://purl.bioontology.org/ontology/MESH/D010891

http://purl.bioontology.org/ontology/MESH/D005475

http://purl.bioontology.org/ontology/MESH/D054659

http://purl.bioontology.org/ontology/MESH/D000069582

http://purl.bioontology.org/ontology/MESH/D010876

http://purl.bioontology.org/ontology/MESH/D000069503

http://purl.bioontology.org/ontology/MESH/D024841

http://purl.bioontology.org/ontology/MESH/D008468

http://purl.bioontology.org/ontology/MESH/D014292

http://purl.bioontology.org/ontology/MESH/D002936

http://purl.bioontology.org/ontology/MESH/D011814

http://purl.bioontology.org/ontology/MESH/D020008

http://purl.bioontology.org/ontology/MESH/D000069458

http://purl.bioontology.org/ontology/MESH/D006919

http://purl.bioontology.org/ontology/MESH/D017300

http://purl.bioontology.org/ontology/MESH/D004049

http://purl.bioontology.org/ontology/MESH/D002354

http://purl.bioontology.org/ontology/MESH/D015765

isa

http://purl.bioontology.org/ontology/MESH/D018491

http://purl.bioontology.org/ontology/MESH/D065127

http://purl.bioontology.org/ontology/MESH/D000928

http://purl.bioontology.org/ontology/MESH/D058825

http://purl.bioontology.org/ontology/MESH/D014150

http://purl.bioontology.org/ontology/MESH/D058830

LT

TRD

Machine permutation

2016; ARIPIPRAZOLE was indexed under QUINOLONES 1995-2015 and under PIPERAZINES 1995-2015

Mapped from

http://purl.bioontology.org/ontology/MESH/C000603935

MDA

20150701

MMR

20180620

MN

D03.633.100.810.835.122

D03.383.606.170

notation

D000068180

PA

D018491

D058825

D058830

D014150

D000928

D065127

prefLabel

Aripiprazole

TERMUI

T279365

T000874920

T000874649

T528594

T279364

T279366

TH

US

NLM (2016)

MX

NLM (1995)

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D015363

http://purl.bioontology.org/ontology/MESH/D010879

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http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
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http://purl.obolibrary.org/obo/CHEBI_31236 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_31236 NIFSTD LOOM
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http://doe-generated-ontology.com/OntoAD#C0299792 ONTOAD LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47403 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47403 NCIT LOOM
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http://purl.bioontology.org/ontology/LNC/LP34967-7 LOINC LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005452 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005452 DMTO LOOM
http://www.semanticweb.org/dellvostro3750/ontologies/2018/2/untitled-ontology-10#aripiprazole HP_O LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148786 NDFRT CUI
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http://www.case.edu/EpSO.owl#Aripiprazole EPSO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU017703 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU017703 LOINC LOOM
http://scai.fraunhofer.de/AlzheimerOntology#aripiprazole ADO LOOM
http://www.drugbank.ca/drugs/DB01238 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/406785006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/RXNORM/89013 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/89013 RXNORM LOOM