loading...| Preferred Name |
Aripiprazole |
|
| Synonyms |
OPC 14597 |
|
| Definitions |
A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000068180 |
|
| altLabel |
OPC 14597 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone Abilify Aripiprazol OPC-14597 |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0299792 C1170019 C0950934 |
|
| DC |
1 |
|
| definition |
A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression. |
|
| DX |
20160101 |
|
| HN |
2016 (1995) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
82VFR53I78 0 |
|
| isa |
http://purl.bioontology.org/ontology/MESH/D058825 http://purl.bioontology.org/ontology/MESH/D000928 http://purl.bioontology.org/ontology/MESH/D065127 http://purl.bioontology.org/ontology/MESH/D014150 |
|
| LT |
TRD |
|
| Machine permutation |
2016; ARIPIPRAZOLE was indexed under QUINOLONES 1995-2015 and under PIPERAZINES 1995-2015 |
|
| Mapped from | ||
| MDA |
20150701 |
|
| MMR |
20180620 |
|
| MN |
D03.383.606.170 D03.633.100.810.835.122 |
|
| notation |
D000068180 |
|
| PA |
D058825 D000928 D065127 D058830 D018491 D014150 |
|
| prefLabel |
Aripiprazole |
|
| TERMUI |
T279366 T279365 T000874920 T000874649 T528594 T279364 |
|
| TH |
US NLM (2016) MX NLM (1995) |
|
| tui |
T109 T121 |
|
| subClassOf |