Preferred Name |
Pegloticase |
|
Synonyms |
Krystexxa |
|
ID |
http://purl.bioontology.org/ontology/MESH/C031545 |
|
altLabel |
Krystexxa polyethylene glycol-uricase Puricase methoxypolyethylene glycol uricase PEG-uricase |
|
cui |
C2350657 C2350656 C2948183 |
|
HM |
D011092 D014503 |
|
II |
D004800 |
|
Inverse of RB |
0 R581OT55EA |
|
LT |
TRD |
|
Mapped to | ||
MDA |
19810911 |
|
MeSH Frequency |
104 |
|
MMR |
20170725 |
|
notation |
C031545 |
|
prefLabel |
Pegloticase |
|
SC |
1 |
|
Scope Statement |
uricase covalently attached to polyethylene glycol, modifying 71% of amino groups & retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid |
|
SRC |
Lancet 1981;2(8241):281 |
|
TERMUI |
T722239 T722240 T129037 T129039 T129038 T787541 |
|
TH |
US NLM (2008) FDA SRS (2017) USAN (2008) NLM (1981) INN (19XX) NLM (2011) |
|
tui |
T116 T126 T121 |
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