Medical Subject Headings

Last uploaded: January 31, 2024
Preferred Name

Pegloticase

Synonyms

Krystexxa

ID

http://purl.bioontology.org/ontology/MESH/C031545

altLabel

Krystexxa

polyethylene glycol-uricase

Puricase

methoxypolyethylene glycol uricase

PEG-uricase

cui

C2350657

C2350656

C2948183

HM

D011092

D014503

II

D004800

Inverse of RB

0

R581OT55EA

LT

TRD

Mapped to

http://purl.bioontology.org/ontology/MESH/D014503

http://purl.bioontology.org/ontology/MESH/D011092

MDA

19810911

MeSH Frequency

104

MMR

20170725

notation

C031545

prefLabel

Pegloticase

SC

1

Scope Statement

uricase covalently attached to polyethylene glycol, modifying 71% of amino groups & retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid

SRC

Lancet 1981;2(8241):281

TERMUI

T722239

T722240

T129037

T129039

T129038

T787541

TH

US

NLM (2008)

FDA SRS (2017)

USAN (2008)

NLM (1981)

INN (19XX)

NLM (2011)

tui

T116

T126

T121

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