Medical Subject Headings

Last uploaded: November 18, 2019
Preferred Name

Multiple Sclerosis

Synonyms

Multiple Sclerosis, Acute Fulminating

Definitions

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

ID

http://purl.bioontology.org/ontology/MESH/D009103

altLabel

Multiple Sclerosis, Acute Fulminating

MS (Multiple Sclerosis)

Sclerosis, Multiple

Disseminated Sclerosis

Sclerosis, Disseminated

AQL

BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI

cui

C0751324

C0026769

DC

1

definition

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

DX

19660101

FX

D009188

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000401

http://purl.bioontology.org/ontology/MESH/Q000150

http://purl.bioontology.org/ontology/MESH/Q000188

http://purl.bioontology.org/ontology/MESH/Q000517

http://purl.bioontology.org/ontology/MESH/Q000201

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000503

http://purl.bioontology.org/ontology/MESH/Q000453

http://purl.bioontology.org/ontology/MESH/Q000208

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000821

http://purl.bioontology.org/ontology/MESH/Q000382

http://purl.bioontology.org/ontology/MESH/Q000601

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000523

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000662

http://purl.bioontology.org/ontology/MESH/Q000151

http://purl.bioontology.org/ontology/MESH/Q000628

http://purl.bioontology.org/ontology/MESH/Q000196

http://purl.bioontology.org/ontology/MESH/Q000534

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000532

http://purl.bioontology.org/ontology/MESH/Q000139

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000175

http://purl.bioontology.org/ontology/MESH/Q000000981

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000473

http://purl.bioontology.org/ontology/MESH/Q000451

http://purl.bioontology.org/ontology/MESH/Q000209

http://purl.bioontology.org/ontology/MESH/Q000178

http://purl.bioontology.org/ontology/MESH/Q000469

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D009188

http://purl.bioontology.org/ontology/MESH/D063308

Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D009188

http://purl.bioontology.org/ontology/MESH/D004684

http://purl.bioontology.org/ontology/MESH/D004681

http://purl.bioontology.org/ontology/MESH/D009471

http://purl.bioontology.org/ontology/MESH/D004673

http://purl.bioontology.org/ontology/MESH/D002549

Mapped from

http://purl.bioontology.org/ontology/MESH/C580329

http://purl.bioontology.org/ontology/MESH/C565621

MDA

19990101

MMR

20100625

MN

C10.314.350.500

C10.114.375.500

C20.111.258.250.500

notation

D009103

prefLabel

Multiple Sclerosis

TERMUI

T366473

T027213

T366472

T027212

TH

UNK (19XX)

NLM (2000)

NLM (1966)

tui

T047

subClassOf

http://purl.bioontology.org/ontology/MESH/D020278

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http://purl.bioontology.org/ontology/ICD9CM/340 ICD9CM CUI
http://purl.bioontology.org/ontology/ICD9CM/340 ICD9CM LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_6a53587b_e5ae_4350_baa8_b4899290b1f9 CVAO LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_6a53587b_e5ae_4350_baa8_b4899290b1f9 STO-DRAFT LOOM
http://purl.bioontology.org/ontology/CSP/2042-2324 CRISP CUI
http://purl.bioontology.org/ontology/CSP/2042-2324 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.114.375.500 RH-MESH LOOM
http://www.projecthalo.com/aura#Multiple-Sclerosis AURA LOOM
http://purl.bioontology.org/ontology/LNC/MTHU020805 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU020805 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LA14298-6 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LA14298-6 LOINC LOOM
http://purl.bioontology.org/ontology/MEDDRA/10013451 MEDDRA CUI
http://purl.bioontology.org/ontology/SCTSPA/192928003 SCTSPA CUI
http://www.ebi.ac.uk/efo/EFO_0003885 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_0003885 CCONT LOOM
http://www.ebi.ac.uk/efo/EFO_0003885 EFO LOOM
http://www.semanticweb.org/ontologies/2012/0/Ontology1325521724189.owl#Multiple_Sclerosis CTO LOOM
http://purl.bioontology.org/ontology/LNC/LA17769-3 LOINC CUI
http://purl.bioontology.org/ontology/MDRFRE/10028245 MDRFRE CUI
http://bioontology.org/projects/ontologies/birnlex#birnlex_12514 BIRNLEX LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C10.314.350.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/ICD10/G35 ICD10 CUI
http://purl.bioontology.org/ontology/ICD10/G35 ICD10 LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8328 OCHV LOOM
http://purl.bioontology.org/ontology/ICPCFRE/N86 ICPCFRE CUI
http://doe-generated-ontology.com/OntoAD#C0026769 ONTOAD LOOM
http://purl.jp/bio/4/id/200906066809474868 IOBC LOOM
http://purl.bioontology.org/ontology/MDRFRE/10039720 MDRFRE CUI
http://purl.bioontology.org/ontology/SNMI/DA-25010 SNMI CUI
http://www.co-ode.org/ontologies/galen#MultipleSclerosis GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000002052 NDFRT CUI
http://uri.neuinfo.org/nif/nifstd/birnlex_12514 NIFDYS LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_12514 NIFSTD LOOM
http://purl.jp/bio/11/pdo/PDO_000171 PDO LOOM
http://purl.bioontology.org/ontology/MDRFRE/10013451 MDRFRE CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C20.111.258.250.500 RH-MESH LOOM
http://localhost/plosthes.2017-1#3453 PLOSTHES LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000691761 PDQ CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000691761 PDQ LOOM
http://purl.bioontology.org/ontology/ICPC2P/N86002 ICPC2P CUI
http://identifiers.org/omim/126200 RETO LOOM
http://identifiers.org/omim/126200 GEXO LOOM
http://identifiers.org/omim/126200 REXO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009103 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCTV2/F20..00 RCTV2 LOOM
http://purl.obolibrary.org/obo/DOID_2377 DTO LOOM
http://purl.obolibrary.org/obo/DOID_2377 CLO LOOM
http://purl.obolibrary.org/obo/DOID_2377 ODAE LOOM
http://purl.obolibrary.org/obo/DOID_2377 DOID LOOM
http://purl.obolibrary.org/obo/DOID_2377 BAO LOOM
http://purl.obolibrary.org/obo/DOID_2377 NIFSTD LOOM
http://purl.bioontology.org/ontology/MEDDRA/10028245 MEDDRA CUI
http://purl.bioontology.org/ontology/MEDDRA/10028245 MEDDRA LOOM
http://www.limics.org/hrdo/rdfns#pat_id_107 HRDO LOOM
http://purl.bioontology.org/ontology/LNC/LA27531-5 LOINC CUI
http://purl.bioontology.org/ontology/ICD10CM/G35 ICD10CM CUI
http://purl.bioontology.org/ontology/ICD10CM/G35 ICD10CM LOOM
http://www.gamuts.net/entity#multiple_sclerosis GAMUTS LOOM
http://purl.bioontology.org/ontology/MEDDRA/10039720 MEDDRA CUI
http://www.semanticweb.org/rjyy/ontologies/2015/5/ESSO#Multiple_Sclerosis EPISEM LOOM
http://www.semanticweb.org/rjyy/ontologies/2015/5/ESSO#Multiple_Sclerosis ESSO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10028053 MEDDRA CUI
http://www.owl-ontologies.com/Ontology1172270693.owl#Multiple_Sclerosis FHHO LOOM
http://purl.bioontology.org/ontology/CST/SCLEROSIS%20MULT COSTART CUI
http://purl.bioontology.org/ontology/CST/SCLEROSIS%20MULT COSTART LOOM
http://purl.bioontology.org/ontology/SCTSPA/24700007 SCTSPA CUI
http://purl.bioontology.org/ontology/ICPC2P/N86001 ICPC2P CUI
http://purl.bioontology.org/ontology/ICPC2P/N86001 ICPC2P LOOM
http://purl.bioontology.org/ontology/RCD/F20.. RCD CUI
http://purl.bioontology.org/ontology/RCD/F20.. RCD LOOM
http://purl.bioontology.org/ontology/MSHFRE/D009103 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D009103 MSHFRE CUI
http://purl.bioontology.org/ontology/SNOMEDCT/24700007 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/24700007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0026769 MEDLINEPLUS CUI
http://www.owl-ontologies.com/NPOntology.owl#DOID_2377 NATPRO LOOM
http://purl.bioontology.org/ontology/MDRFRE/10028053 MDRFRE CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3243 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3243 NCIT LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Multiple_Sclerosis APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Multiple_Sclerosis APAONTO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Multiple_Sclerosis APADISORDERS LOOM
http://radlex.org/RID/RID28801 RADLEX LOOM
http://purl.obolibrary.org/obo/MONDO_0005301 MONDO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/192928003 SNOMEDCT CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Multiple_Sclerosis CSEO LOOM