Microbial Conditions Ontology

Last uploaded: September 4, 2019
Preferred Name

norfloxacin

Synonyms

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

OGJPXUAPXNRGGI-UHFFFAOYSA-N

319.133

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

319.33080

norfloxacino

norfloxacinum

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

0

NFLX

C16H18FN3O3

norfloxacin

CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1

norfloxacine

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

Definitions

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

ID

http://purl.obolibrary.org/obo/CHEBI_100246

database_cross_reference

DrugBank:DB01059

Patent:BE863429

Patent:US4292317

PMID:6234465

PMID:6461606

Gmelin:1576626

PMID:6211142

Reaxys:567897

PMID:3908074

Patent:DE2840910

KEGG:D00210

PMID:6454381

KEGG:C06687

PMID:6224685

Patent:US4146719

Beilstein:567897

LINCS:LSM-5286

colombos:NORFLOXACIN

CAS:70458-96-7

PMID:3317294

Drug_Central:1967

Wikipedia:Norfloxacin

HMDB:HMDB15192

definition

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

has exact synonym

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

has role

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_78298

http://purl.obolibrary.org/obo/CHEBI_59517

has_alternative_id

CHEBI:7629

has_obo_namespace

chebi_ontology

has_related_synonym

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

OGJPXUAPXNRGGI-UHFFFAOYSA-N

319.133

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

319.33080

norfloxacino

norfloxacinum

0

NFLX

C16H18FN3O3

norfloxacin

CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1

norfloxacine

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

id

CHEBI:100246

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

label

norfloxacin

notation

CHEBI:100246

prefLabel

norfloxacin

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_87211

http://purl.obolibrary.org/obo/CHEBI_26512

http://purl.obolibrary.org/obo/CHEBI_23765

http://purl.obolibrary.org/obo/CHEBI_86324

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http://purl.obolibrary.org/obo/ARO_3000662 ARO LOOM
http://purl.obolibrary.org/obo/ARO_3000662 ARO LOOM
http://purl.bioontology.org/ontology/NDDF/002881 NDDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028365 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/eg9.. RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147623 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907005654892930 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009643 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Norfloxacin GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP16156-9 LOINC LOOM
http://id.loc.gov/authorities/subjects/sh85092409 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/VANDF/4019503 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 PHIPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_100246 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100246 CHEBI SAME_URI
http://purl.bioontology.org/ontology/SNOMEDCT/387271008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8772 OCHV LOOM
http://purl.jp/bio/4/id/200906042016138690 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/S01AE02 ATC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008461 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.374 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-55730 SNMI LOOM
http://purl.bioontology.org/ontology/UATC/J01MA06 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D009643 MESH LOOM
http://www.drugbank.ca/drugs/DB01059 FTC LOOM
http://d-nb.info/gnd/4243995-4 FAST-TOPICAL LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147623 ODAE LOOM
http://purl.bioontology.org/ontology/RXNORM/7517 RXNORM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47638 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47638 NCIT LOOM