Preferred Name |
darunavir |
|
Synonyms |
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate DRV Darunavir TMC114 |
|
Definitions |
An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. source: http://purl.obolibrary.org/obo/CHEBI_367163 |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_367163 |
|
definition |
An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. source: http://purl.obolibrary.org/obo/CHEBI_367163 |
|
exact_synonym |
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate DRV Darunavir TMC114 |
|
label |
darunavir |
|
prefixIRI |
obolibrary:CHEBI_367163 |
|
prefLabel |
darunavir |
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source | ||
subClassOf |