Human Phenotype Ontology

Last uploaded: April 15, 2019
Preferred Name

Pulmonic stenosis

Synonyms

Pulmonic valve stenosis

Pulmonary stenosis

Narrowing of pulmonic valve

Pulmonary valve stenosis

Definitions

A narrowing of the right ventricular outflow tract that can occur at the pulmonary valve (valvular stenosis) or just below the pulmonary valve (infundibular stenosis). Infundibular pulmonic stenosis is mostly caused by overgrowth of the heart muscle wall (hypertrophy of the septoparietal trabeculae). Pulmonic stenosis is often seen as a part of Fallot' s tetralogy, in which case the events leading to the formation of the overriding aorta are also believed to be a cause of the pulmonic stenosis. The pulmonic stenosis is the major cause of the malformations seen in patients with Fallot tetralogy, with the other associated malformations acting as compensatory mechanisms to the pulmonic stenosis. The degree of stenosis varies between individuals with TOF, and is the primary determinant of symptoms and severity. This malformation is infrequently described as sub-pulmonary stenosis or subpulmonary obstruction.

ID

http://purl.obolibrary.org/obo/HP_0001642

comment

Infundibular pulmonic stenosis is mostly caused by overgrowth of the heart muscle wall (hypertrophy of the septoparietal trabeculae). Pulmonic stenosis is often seen as a part of Fallot' s tetralogy, in which case the events leading to the formation of the overriding aorta are also believed to be a cause of the pulmonic stenosis. The pulmonic stenosis is the major cause of the malformations seen in patients with Fallot tetralogy, with the other associated malformations acting as compensatory mechanisms to the pulmonic stenosis. The degree of stenosis varies between individuals with TOF, and is the primary determinant of symptoms and severity. This malformation is infrequently described as sub-pulmonary stenosis or subpulmonary obstruction.

database_cross_reference

UMLS:C1956257

SNOMEDCT_US:56786000

MSH:D011666

Fyler:1611

definition

A narrowing of the right ventricular outflow tract that can occur at the pulmonary valve (valvular stenosis) or just below the pulmonary valve (infundibular stenosis).

has_exact_synonym

Pulmonic valve stenosis

Pulmonary stenosis

Narrowing of pulmonic valve

Pulmonary valve stenosis

has_obo_namespace

human_phenotype

id

HP:0001642

label

Pulmonic stenosis

notation

HP:0001642

prefLabel

Pulmonic stenosis

treeView

http://purl.obolibrary.org/obo/HP_0031654

subClassOf

http://purl.obolibrary.org/obo/HP_0031654

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/265500 OMIM LOOM
http://purl.bioontology.org/ontology/MEDDRA/10037460 MEDDRA LOOM
http://www.gamuts.net/entity#pulmonic_valve_stenosis GAMUTS REST
http://purl.obolibrary.org/obo/HP_0001642 EFO LOOM
http://purl.obolibrary.org/obo/HP_0001642 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 CCONT LOOM
http://purl.obolibrary.org/obo/HP_0001642 CCONT SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 EFO LOOM
http://purl.obolibrary.org/obo/HP_0001642 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 EFO LOOM
http://purl.obolibrary.org/obo/HP_0001642 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 EFO LOOM
http://purl.obolibrary.org/obo/HP_0001642 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 HOOM SAME_URI
http://purl.obolibrary.org/obo/HP_0001642 UPHENO LOOM
http://purl.obolibrary.org/obo/HP_0001642 UPHENO SAME_URI
http://purl.bioontology.org/ontology/CST/STENO%20PULM COSTART LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU001440 OMIM LOOM
http://www.gamuts.net/entity#pulmonic_stenosis GAMUTS REST
http://www.gamuts.net/entity#pulmonic_stenosis GAMUTS LOOM
http://purl.org/obo/owl/HP#HP_0001642 BDO LOOM