loading...| Preferred Name |
Erythromycin |
|
| Synonyms |
|
|
| Definitions |
Erythromycin is a macrolide antibiotic with a 14-carbon ring that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people that have an allergy to penicillins. Erythromycin may possess bacteriocidal activity, particularly at higher concentrations by binding to the 50S subunit of the bacterial 70S rRNA complex, inhibiting peptidyl-tRNA translocation. Thus, protein synthesis and subsequently structure/function processes critical for life or replication are inhibited. |
|
| ID |
http://purl.obolibrary.org/obo/HIO_0000282 |
|
| description |
Erythromycin is a macrolide antibiotic with a 14-carbon ring that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people that have an allergy to penicillins. Erythromycin may possess bacteriocidal activity, particularly at higher concentrations by binding to the 50S subunit of the bacterial 70S rRNA complex, inhibiting peptidyl-tRNA translocation. Thus, protein synthesis and subsequently structure/function processes critical for life or replication are inhibited. |
|
| created_by |
Jade Hotchkiss |
|
| creation_date |
2019-08-01T07:45:46.53341Z |
|
| database cross reference |
ARO:0000006 |
|
| definition source | ||
| existence in other ontologies |
Sufficient |
|
| hasExactSynonym |
Erythromycin A Erythromycine N-methylerythromycin A Eritromicina Erythromycinum Abomacetin Emgel Erymax Erythrocin |
|
| label |
Erythromycin |
|
| prefixIRI |
HIO:0000282 |
|
| prefLabel |
Erythromycin |
|
| subClassOf |