loading...| Preferred Name |
mucocutaneous lymph node syndrome |
|
| Synonyms |
Kawasaki syndrome Kawasaki disease Kawasaki's disease acute febrile mucocutaneous lymph node syndrome mucocutaneous lymph node syndrome acute febrile mucocutaneous lymph node syndrome [MCLS] acute febrile MCLS MLNS infantile polyarteritis nodosa Kd infantile polyarteritis |
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| Definitions |
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities. Kawasaki disease (KD) is a febrile, systemic, self-limiting vasculitis affecting children and characterized by inflammation in the medium sized vessels associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated. KD is the most common cause of acquired heart disease in children in developed countries and is a risk factor for ischemic heart disease in adulthood. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0004246 |
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| closeMatch | ||
| database_cross_reference |
MedDRA:10028083 MeSH:D009080 NCIt:C34825 OMIM:611775 MedDRA:10023320 Orphanet:2331 GARD:6816 MESH:D009080 NCIT:C34825 UMLS:C0026691 MONDO:0012727 SCTID:75053002 ICD9:446.1 DOID:13378 |
|
| definition |
An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities. Kawasaki disease (KD) is a febrile, systemic, self-limiting vasculitis affecting children and characterized by inflammation in the medium sized vessels associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated. KD is the most common cause of acquired heart disease in children in developed countries and is a risk factor for ischemic heart disease in adulthood. |
|
| exactMatch |
http://identifiers.org/mesh/D009080 http://purl.obolibrary.org/obo/DOID_13378 http://identifiers.org/snomedct/75053002 http://purl.obolibrary.org/obo/Orphanet_2331 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
Kawasaki syndrome Kawasaki disease Kawasaki's disease acute febrile mucocutaneous lymph node syndrome mucocutaneous lymph node syndrome acute febrile mucocutaneous lymph node syndrome [MCLS] acute febrile MCLS MLNS infantile polyarteritis nodosa |
|
| has_related_synonym |
Kawasaki syndrome Kawasaki disease Kd infantile polyarteritis |
|
| id |
EFO:0004246 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare |
|
| label |
mucocutaneous lymph node syndrome |
|
| notation |
EFO:0004246 |
|
| prefLabel |
mucocutaneous lymph node syndrome |
|
| term editor |
Dani Welter |
|
| subClassOf |
http://www.ebi.ac.uk/efo/EFO_0000508 |