Experimental Factor Ontology

Last uploaded: March 18, 2024
Preferred Name

nebivolol

Synonyms

(1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol

(1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}

dl-nebivolol

nebivolol

nebivololum

Definitions

A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure.

ID

http://purl.obolibrary.org/obo/CHEBI_64022

database_cross_reference

ChemIDplus:118457-14-0

CiteXplore:18786089

SNOMEDCT:318638009

CiteXplore:18221115

Reaxys:4789059

CiteXplore:20620250

CiteXplore:18083889

CiteXplore:19443516

NCIt:C66221

CiteXplore:19815121

SNOMEDCT:395808005

CiteXplore:17661735

MeSH:C052753

KEGG DRUG:D05127

CiteXplore:18078016

DrugBank:DB04861

PMID:18078016

PMID:19815121

PMID:18221115

CAS:118457-14-0

PMID:18083889

PMID:23314750

PMID:17661735

PMID:20620250

Patent:US4654362

Wikipedia:Nebivolol

KEGG:D05127

PMID:19443516

PMID:18786089

definition

A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure.

has_obo_namespace

chebi_ontology

has_related_synonym

(1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol

(1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}

dl-nebivolol

nebivolol

nebivololum

id

CHEBI:64022

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

label

nebivolol

notation

CHEBI:64022

prefLabel

nebivolol

subClassOf

http://purl.obolibrary.org/obo/CHEBI_24431

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_64022 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 HSPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_64022 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 HSPO LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_64022 CHEBI LOOM
http://stirdf.jst.go.jp/id/200907003717144014 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Nebivolol GALEN LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66221 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/C07AB12 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015627 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_64019 FIDEO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176131 NDFRT LOOM
http://www.drugbank.ca/drugs/DB04861 FTC LOOM
http://purl.bioontology.org/ontology/RXNORM/31555 RXNORM LOOM
http://purl.obolibrary.org/obo/MESH_D000068577 BERO LOOM
http://bmi.utah.edu/ontologies/hfontology/C0068475 HFO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C052753 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14478 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0001294 OMIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0068475 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4027169 VANDF LOOM
https://go.drugbank.com/drugs/DB04861 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D000068577 MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C66221 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395808005 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906016651798736 IOBC LOOM