Preferred Name |
Losartan |
|
Synonyms |
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol Losartan 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol losartan |
|
Definitions |
A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_6541 |
|
charge |
0 |
|
database_cross_reference |
Patent:US5138069 DrugBank:DB00678 PMID:31893179 KEGG:C07072 KEGG:D08146 Drug_Central:1610 Patent:EP253310 PMID:31636311 PMID:18940180 PMID:18800458 PMID:18800451 PMID:18800450 PMID:12561964 Wikipedia:Losartan PMID:31299855 Beilstein:4770867 Reaxys:4770867 LINCS:LSM-3701 CAS:114798-26-4 HMDB:HMDB0014816 PMID:32048541 PMID:31613648 PMID:11589260 PMID:11115412 PMID:15703421 |
|
definition |
A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position |
|
formula |
C22H22ClN6O.K C22H23ClN6O |
|
has role |
http://purl.obolibrary.org/obo/CHEBI_61016 http://purl.obolibrary.org/obo/CHEBI_38070 |
|
has_exact_synonym |
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol Losartan |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol losartan |
|
has_RxCUI |
52175 |
|
id |
CHEBI:6541 |
|
in_subset | ||
inchi |
InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) |
|
inchikey |
PSIFNNKUMBGKDQ-UHFFFAOYSA-N |
|
is conjugate acid of | ||
is_bearer_of | ||
label |
Losartan losartan |
|
mass |
422.91100 |
|
monoisotopicmass |
422.16219 |
|
notation |
CHEBI:6541 |
|
prefLabel |
Losartan |
|
smiles |
CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
|
subClassOf |